Evidence map›Paper›PMID 31171630›Full record

ArticleThe Journal of cell biology2019

ISM1 regulates NODAL signaling and asymmetric organ morphogenesis during development.

Liliana Osório, Xuewei Wu, Linsheng Wang, Zhixin Jiang, Carlos Neideck, Guojun Sheng, Zhongjun Zhou

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of cell biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Science advances · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Advances in research of biological functions of Isthmin-1.Journal of cell communication and signaling · 2023
    Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Identification ofFrontiers in genetics · 2022
    Article
  16. A brief overview about the adipokine: Isthmin-1.Frontiers in cardiovascular medicine · 2022
    Review
  17. Isthmin 1 - a novel insulin-like adipokine.Nature reviews. Endocrinology · 2021
    Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 3 countries.

Liliana Osório *School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong.ORCID 0000-0002-7996-5635
Xuewei Wu *School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong.
Linsheng Wang *School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong.
Zhixin JiangSchool of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong.
Carlos NeideckSchool of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong.ORCID 0000-0002-6367-3320
Guojun ShengInternational Research Center for Medical Sciences, Kumamoto University, Kumamoto, Japan.ORCID 0000-0001-6759-3785
Zhongjun ZhouSchool of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong zhongjun@hku.hk.ORCID 0000-0001-7092-8128
Chinese University of Hong Kong · HKKumamoto University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Isthmin1 (ISM1) was originally identified as a fibroblast group factor expressed in

Indexed as

ActivinsAnimalsBody PatterningBone Morphogenetic Protein 4Chick EmbryoGene Expression Regulation, DevelopmentalHEK293 CellsHeLa CellsHumansIn Situ HybridizationMesodermMiceMorphogenesisNodal ProteinSignal TransductionThrombospondinsactivin AActivinsBMP4 protein, humanBone Morphogenetic Protein 4ISM1 protein, humanNodal ProteinNODAL protein, humanThrombospondinsTransforming Growth Factor beta1

Identifiers

PMID31171630
PMCPMC6605798
OpenAlexW2955577379

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.