Evidence map›Paper›PMID 31171596›Full record

Trial reportJournal of nuclear medicine : official publication, Society of Nuclear Medicine2019

A Fully Automatic Technique for Precise Localization and Quantification of Amyloid-β PET Scans.

Mouna Tahmi, Wassim Bou-Zeid, Qolamreza R Razlighi

Abstract readClinical Trial, Phase III
In one paragraph

Trial report in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

  1. Article
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  8. Comparison of two preprocessing methods forEuropean journal of nuclear medicine and molecular imaging · 2025
    Article
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  13. Ultra-fast [EJNMMI physics · 2024
    Article
  14. Voxel-based evaluation for [Quantitative imaging in medicine and surgery · 2024
    Article
  15. Article
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  18. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Mouna TahmiDepartment of Neurology, Columbia University Medical Center, New York, New York; and mt3288@cumc.columbia.edu.
Wassim Bou-ZeidDepartment of Neurology, Columbia University Medical Center, New York, New York; and.
Qolamreza R RazlighiDepartment of Neurology, Columbia University Medical Center, New York, New York; and.

Funding

Functional Connectivity Network in default mode regions provides the underlying infrastructure for task-based functional co-de/activation networksR01AG057962 · NIA · WEILL MEDICAL COLL OF CORNELL UNIV · PI RAZLIGHI, QOLAMREZA RAY · 2018 to 2022
$4.0M
NIA NIH HHS R01 AG057962
6 · The paper itself

Abstract

Spatial heterogeneity in the accumulation of amyloid-β plaques throughout the brain during asymptomatic as well as clinical stages of Alzheimer disease calls for precise localization and quantification of this protein using PET imaging. To address this need, we have developed and evaluated a technique that quantifies the extent of amyloid-β pathology on a millimeter-by-millimeter scale in the brain with unprecedented precision using data from PET scans.

Indexed as

Image Processing, Computer-AssistedPositron-Emission TomographyAgedAged, 80 and overAmyloid beta-PeptidesAutomationFemaleHumansMaleMiddle AgedAmyloid beta-Peptides18F-florbetaben PETAlzheimer diseaseamyloid-βFreeSurferspatial normalization

Identifiers

PMID31171596
PMCPMC6894379

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.