Evidence map›Paper›PMID 31171382›Full record

ArticleTrends in neurosciences2019

Studying Laboratory Mice - Into the Wild.

Julie C Savage, Marie-Ève Tremblay

Abstract readComment
PubMed Publisher
In one paragraph

Article in Trends in neurosciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Beyond the Lab: Cognitive Neuroscience in Real-World Contexts.Wiley interdisciplinary reviews. Cognitive science
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Julie C SavageNeurosciences Axis, Centre de recherche du CHU de Québec, 2705 Boulevard Laurier, Québec, G1V 4G2, Canada.
Marie-Ève TremblayNeurosciences Axis, Centre de recherche du CHU de Québec, 2705 Boulevard Laurier, Québec, G1V 4G2, Canada. Electronic address: tremblay.marie-eve@crchudequebec.ulaval.ca.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Studies using rewilded laboratory mice have begun to provide important clues into the complex relationship between environment, immunity, and behavior. In a recent paper, Cope and colleagues (Hippocampus, 2019) showed that exposing laboratory mice to outdoor living, either with or without peripheral worm infection, increased adult neurogenesis and had major effects on microglia, but only outdoor living coupled with worm infection increased anxiety.

Indexed as

HippocampusNematode InfectionsAnimalsAnxietyMiceMicrogliaNeurogenesisanxietymicroglianeurogenesisphagocytosis

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.