Evidence map›Paper›PMID 31171344›Full record

ArticleJournal of the National Medical Association2019

Racial Disparities in Adult Pneumococcal Vaccination Indications and Pneumococcal Hospitalizations in the U.S.

Mary Patricia Nowalk, Angela R Wateska, Chyongchiou Jeng Lin, William Schaffner, Lee H Harrison, Richard K Zimmerman, Kenneth J Smith

Abstract readComparative Study
In one paragraph

Article in Journal of the National Medical Association, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Article
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  5. Review
  6. Vaccine uptake and hesitancy among Black people: A scoping review.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2026
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  15. Association Between Social Vulnerability and Streptococcus pneumoniae Antimicrobial Resistance in US Adults.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024
    Article
  16. Pneumococcal Vaccination Strategies in 50-Year-Olds to Decrease Racial Disparities: A US Societal Perspective Cost-Effectiveness Analysis.Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mary Patricia NowalkUniversity of Pittsburgh School of Medicine, Pittsburgh PA, USA.
Angela R WateskaUniversity of Pittsburgh School of Medicine, Pittsburgh PA, USA.
Chyongchiou Jeng LinUniversity of Pittsburgh School of Medicine, Pittsburgh PA, USA.
William SchaffnerVanderbilt University School of Medicine, Nashville TN, USA.
Lee H HarrisonUniversity of Pittsburgh School of Medicine, Pittsburgh PA, USA.
Richard K ZimmermanUniversity of Pittsburgh School of Medicine, Pittsburgh PA, USA.
Kenneth J SmithUniversity of Pittsburgh School of Medicine, Pittsburgh PA, USA.

Funding

Analyzing Adult Pneumococcal Vaccination Implementation in the UnderservedR01AI116575 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SMITH, KENNETH J · 2016 to 2023
$2.8M
NIAID NIH HHS R01 AI116575
6 · The paper itself

Abstract

backgroundRacial disparities in U.S. adult pneumococcal vaccination rates persist despite reduced barriers to access. Consequently, racial and ethnic minorities experience pneumococcal disease at higher rates than whites. This study examined prevalence of high-risk conditions and pneumococcal hospitalizations among U.S. black and non-black populations aged ≥50 years.

methodsNational Health Interview Survey, National Center for Health Statistics and National Inpatient Sample data were used to create black and non-black population cohorts, determine risk factors for pneumococcal disease (pneumococcal vaccine indications) and assess the impact of pneumococcal hospitalization. Each racial cohort was segmented into groups based on the presence of immunocompromising or other pneumococcal high-risk conditions. Persons without those conditions were separated into smokers (also a pneumococcal vaccine indication) and nonsmokers. Mortality was estimated from NCHS life table data. NIS data provided length of stay and costs (calculated from cost to charge ratios) for admissions related to pneumococcal disease including bacteremia, meningitis and nonbacteremic pneumonia.

resultsThere were similar proportions of immunocompromised (<5%) and smokers (14%) in both racial cohorts. Likelihood of non-immunocompromising pneumococcal high-risk conditions was higher for blacks than non-blacks at age 65, but higher for non-blacks than blacks at age 80 years (P < 0.001). Age-specific relative likelihood of mortality was 1.1%-12% higher in blacks than non-blacks (P < 0.001). Length of stay was significantly longer for blacks than non-blacks in all age and discharge status groups for non-bacteremic pneumonia and for blacks discharged alive with invasive pneumococcal disease. Costs were higher for blacks 65 years or older with invasive pneumococcal disease.

conclusionMarked differences exist between U.S. black and non-black populations in likelihood of conditions conferring a high-risk of pneumococcal disease, and for length of stay and costs of pneumococcal disease hospitalizations. Further research is recommended to identify cost-effective policies or interventions to increase vaccine uptake in higher risk populations.

Indexed as

Pneumococcal VaccinesAgedAged, 80 and overAge FactorsBlack or African AmericanFemaleHealth Care CostsHealthcare DisparitiesHealth SurveysHumansImmunocompromised HostLength of StayMaleMiddle AgedPatient DischargePneumococcal InfectionsPneumococcal VaccinesDisparitiesPneumococcal diseasePneumococcal vaccineRace

Identifiers

PMID31171344
PMCPMC6888932

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.