Evidence map›Paper›PMID 31170979›Full record

ArticleBMC complementary and alternative medicine2019

Antibacterial and antibiotic-modifying activities of fractions and compounds from Albizia adianthifolia against MDR Gram-negative enteric bacteria.

Cedric F Tchinda, Gaiëlle Sonfack, Ingrid K Simo, İlhami Çelik, Igor K Voukeng, Blaise K Nganou, Gabin T M Bitchagno, Sultan Funda Ekti, Mathieu Tene, Pierre Tane and 2 more

Open access · goldAbstract read
In one paragraph

Article in BMC complementary and alternative medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 24 citations in OpenAlex.

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  6. Toward the Allelopathy ofFrontiers in plant science · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Cedric F TchindaDepartment of Biochemistry, Faculty of Science, University of Dschang, P.O. Box 67, Dschang, Cameroon.
Gaiëlle SonfackDepartment of Chemistry, Faculty of Science, University of Dschang, Dschang, Cameroon.
Ingrid K SimoDepartment of Chemistry, Faculty of Science, University of Dschang, Dschang, Cameroon.
İlhami ÇelikDepartment of Chemistry, Faculty of Science, Eskişehir Technical University, 26470, Eskişehir, Turkey.
Igor K VoukengDepartment of Biochemistry, Faculty of Science, University of Dschang, P.O. Box 67, Dschang, Cameroon.
Blaise K NganouDepartment of Chemistry, Faculty of Science, University of Dschang, Dschang, Cameroon.
Gabin T M BitchagnoDepartment of Chemistry, Faculty of Science, University of Dschang, Dschang, Cameroon.
Sultan Funda EktiDepartment of Chemistry, Faculty of Science, Eskişehir Technical University, 26470, Eskişehir, Turkey.
Mathieu TeneDepartment of Chemistry, Faculty of Science, University of Dschang, Dschang, Cameroon.
Pierre TaneDepartment of Chemistry, Faculty of Science, University of Dschang, Dschang, Cameroon.
Veronique P BengDepartment of Biochemistry, Faculty of Science, University of Yaounde I, Yaounde, Cameroon.
Victor KueteDepartment of Biochemistry, Faculty of Science, University of Dschang, P.O. Box 67, Dschang, Cameroon. kuetevictor@yahoo.fr.
Université de Dschang · CMEskisehir Technical University · TRUniversité de Yaoundé I · CM

Funding

Anadolu Üniversitesi 1306F110
6 · The paper itself

Abstract

backgroundAlbizia adianthifolia (Schum.) is medicinally used in Cameroon to manage bronchitis and skin diseases. Our previous study documented the antibacterial potential of its roots' methanol extract. In this study, methanol roots extract was subjected to chromatography techniques and fractions (AARa and AARb), sub-fractions (AARa1-4, AARb1-2 and AARb11-14) together with isolated phytochemicals were assessed for their antimicrobial as well as their antibiotic-potentiating effects towards Gram-negative multidrug resistant (MDR) bacteria.

methodsThe antibacterial activities of the samples (determination of Minimal Inhibitory « MIC » and Minimal Bactericidal Concentration « MBC ») were determined by the modified rapid p-iodonitrotetrazolium chloride (INT) colorimetric assay, as well as those of antibiotics in association with the compounds. Column chromatography was applied to isolate phytochemicals from roots extract and their chemical structures were determined using spectroscopic techniques.

resultsThe phytochemicals isolated were stearic acid (1), a mixture (1:1) of stigmasterol and β-sitosterol (2 +  3), β-sitosterol 3-O-β-

conclusionThe present study provides information on the possible use of Albizia adianthifolia and its constituents in the control of Gram-negative infections including MDR phenotypes.

Indexed as

Drug SynergismAlbizziaAnti-Bacterial AgentsDrug Resistance, Multiple, BacterialMicrobial Sensitivity TestsPhytochemicalsAnti-Bacterial AgentsPhytochemicalsAlbizia adianthifoliaAntibiotic modifying activityFabaceaeMulti-drug resistancePhytochemicals

Identifiers

PMID31170979
PMCPMC6554897
OpenAlexW2948262633

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.