Evidence map›Paper›PMID 31170939›Full record

ArticleBMC pediatrics2019

Low head circumference during early childhood and its predictors in a semi-urban settlement of Vellore, Southern India.

Kulandaipalayam Natarajan Sindhu, Prashanth Ramamurthy, Karthikeyan Ramanujam, Ankita Henry, Joseph Dian Bondu, Sushil Mathew John, Sudhir Babji, Beena Koshy, Anuradha Bose, Gagandeep Kang and 1 more

Open access · goldAbstract read
In one paragraph

Article in BMC pediatrics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 37 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Kulandaipalayam Natarajan SindhuDivision of Gastrointestinal Sciences, Christian Medical College, Vellore, Tamil Nadu, India.
Prashanth RamamurthyRural Unit for Health and Social Affairs, Christian Medical College, Vellore, Tamil Nadu, 632 209, India. drprashanth@cmcvellore.ac.in.
Karthikeyan RamanujamDivision of Gastrointestinal Sciences, Christian Medical College, Vellore, Tamil Nadu, India.
Ankita HenryDivision of Gastrointestinal Sciences, Christian Medical College, Vellore, Tamil Nadu, India.
Joseph Dian BonduDepartment of Clinical Biochemistry, Christian Medical College, Vellore, Tamil Nadu, India.
Sushil Mathew JohnLow Cost Effective Care Unit, Christian Medical College, Vellore, Tamil Nadu, India.
Sudhir BabjiDivision of Gastrointestinal Sciences, Christian Medical College, Vellore, Tamil Nadu, India.
Beena KoshyDevelopmental Pediatric Unit, Christian Medical College, Vellore, Tamil Nadu, India.
Anuradha BoseDepartment of Community Health, Christian Medical College, Vellore, Tamil Nadu, India.
Gagandeep KangDivision of Gastrointestinal Sciences, Christian Medical College, Vellore, Tamil Nadu, India.
Venkata Raghava MohanDepartment of Community Health, Christian Medical College, Vellore, Tamil Nadu, India.
Christian Medical College & Hospital · INChristian Medical College · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundStunting in developing countries continues to be a major public health problem. Measuring head circumference (HC) during clinical anthropometric assessment can help predict stunting. The aim of this study was to assess burden and determine the predictors of low HC (<- 2 SD) at birth and during first 2 years of life in a semi- urban settlement of Vellore.

methodsThe study uses baseline data and serial HC measurements from the birth cohort of MAL-ED study, where 228 children from Vellore completed follow-up between March 2010 to February 2014. Analysis of baseline, maternal and paternal characteristics, micro-nutrient status and cognition with HC measurements was performed using STATA version 13.0 software.

resultsThe mean HC (±SD) at 1st, 12th and 24th month were 33.37 (1.29) cm, 42.76 (1.23) cm and 44.9 (1.22) cm respectively. A third of the infants (75/228) had HC less than - 2 SD at first month of life, and on follow-up, 50% of the cohort had HC ≤ -2 SD both at 12th and 24th month. Low HC measurements at all three time-points were observed for 21.6% (46/222) infants. Low HC was significantly associated with stunting in 37.3% (OR = 10.8), 57.3% (OR = 3.1) and 44.4% (OR = 2.6) children at 1st, 12th and 24th month respectively. Bivariate analysis of low HC (<- 2 SD) at 12th month showed a statistically significant association with lower socioeconomic status, low paternal and maternal HC and low maternal IQ. Multivariable logistic regression analysis showed maternal (AOR = 0.759, 95% CI = 0.604 to 0.954) and paternal (AOR = 0.734, 95% CI = 0.581 to 0.930) HC to be significantly associated with HC attained by the infant at the end of 12 months.

conclusionsOne-third of the children in our cohort had low head circumference (HC) at birth, with one-fifth recording low HC at all time-points until 2 years of age. Low HC was significantly associated with stunting. Paternal and maternal HC predicted HC in children. HC measurement, often less used, can be a simple tool that can be additionally used by clinicians as well as parents/caregivers to monitor child growth.

Indexed as

CephalometryAge FactorsBody Mass IndexCohort StudiesFemaleGrowth DisordersHeadHumansIndiaInfantIntelligenceMaleMalnutritionMaternal AgeMicronutrientsOdds RatioMicronutrientsGrowthHead circumference measurementIndiaMaternal head circumferenceNutritionPaternal head circumference

Identifiers

PMID31170939
PMCPMC6552319
OpenAlexW2948533104

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.