Evidence map›Paper›PMID 31170922›Full record

ArticleBMC medical research methodology2019

Feasibility of identifying important changes in care management resulting from cardiovascular magnetic resonance (CMR) using hospital episode data in patients who activate the primary percutaneous coronary intervention (PPCI) pathway.

Maria Pufulete, Jessica Harris, Stephen Dorman, Lynn Cook, Chiara Bucciarelli-Ducci, John P Greenwood, Richard Anderson, Rachel Brierley, Barnaby C Reeves

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in BMC medical research methodology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Maria PufuleteClinical Trials and Evaluation Unit, University of Bristol, Level 7, Bristol Royal Infirmary, Queen's Building, Bristol, UK. maria.pufulete@bristol.ac.uk.ORCID http://orcid.org/0000-0002-1775-1949
Jessica HarrisClinical Trials and Evaluation Unit, University of Bristol, Level 7, Bristol Royal Infirmary, Queen's Building, Bristol, UK.
Stephen DormanNIHR Bristol Cardiovascular Research Unit, Bristol Heart Institute, University of Bristol, Bristol, UK.
Lynn CookDepartment of Information Management & Technology, University Hospitals Bristol NHS Foundation Trust, Bristol, UK.
Chiara Bucciarelli-DucciNIHR Bristol Cardiovascular Research Unit, Bristol Heart Institute, University of Bristol, Bristol, UK.
John P GreenwoodMultidisciplinary Cardiovascular Research Centre and Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, UK.
Richard AndersonUniversity Hospitals of Wales, Heath Park, Cardiff, UK.
Rachel BrierleyClinical Trials and Evaluation Unit, University of Bristol, Level 7, Bristol Royal Infirmary, Queen's Building, Bristol, UK.
Barnaby C ReevesClinical Trials and Evaluation Unit, University of Bristol, Level 7, Bristol Royal Infirmary, Queen's Building, Bristol, UK.
Bristol Royal Infirmary · GBUniversity of Bristol · GBUniversity Hospital of Wales · GBUniversity Hospitals Bristol NHS Foundation Trust · GBUniversity of Leeds · GB

Funding

British Heart FoundationDepartment of Health 11/2003/58
6 · The paper itself

Abstract

backgroundWe determined whether it is feasible to identify important changes in care management resulting from cardiovascular magnetic resonance (CMR) in patients who activate the primary percutaneous coronary intervention (PPCI) pathway from hospital episode data, in order to construct a composite primary outcome (hypothesised to reduce the risk of major adverse cardiac-related events, MACE) to compare patients exposed to CMR or not.

methodsWe used Hospital Episode Statistics (HES) and Patient Episode Database for Wales (PEDW) to identify clinical events that reflected important changes in management in the year following the index admission in five subgroups of patients who activated the PPCI pathway recruited as part of a feasibility cohort study (n = 1655 with HES/PEDW data). For all subgroups, we identified frequency of events and time to the first event for each change in management.

resultsWe identified all clinical events (new diagnoses, additional diagnostic tests and procedures) except for medication prescriptions. Diagnostic tests were underestimated because most are carried out in outpatient clinics and outpatient datasets had missing procedure codes for 74% of patients (some tests done in hospital may also not be recorded). We successfully tabulated frequencies of events and distributions of times to first event for most changes in management by CMR status and in CMR / non CMR centres.

conclusionsIt is feasible to identify changes in care management between patients who have / do not have CMR within relevant patient subgroups. Further work to derive a weighting algorithm is required before attempting to combine the events in a composite endpoint.

Indexed as

Coronary AngiographyElectronic Health RecordsFeasibility StudiesHospital RecordsHumansMagnetic Resonance AngiographyMyocardial InfarctionPatient Care ManagementPercutaneous Coronary InterventionTreatment OutcomeCardiovascular magnetic resonance (CMR)EnglandHospital Episode Statistics (HES)Patient episode database Wales (PEDW)Primary percutaneous coronary intervention (PPCI)

Identifiers

PMID31170922
PMCPMC6554929
OpenAlexW2948808672

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.