Evidence map›Paper›PMID 31170679›Full record

ArticleRedox biology2019

Redox properties and human serum albumin binding of nitro-oleic acid.

Martina Zatloukalova, Milos Mojovic, Aleksandra Pavicevic, Martin Kabelac, Bruce A Freeman, Michaela Pekarova, Jan Vacek

Open access · goldAbstract read
In one paragraph

Article in Redox biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
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  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 3 countries.

Martina ZatloukalovaDepartment of Medical Chemistry and Biochemistry, Faculty of Medicine and Dentistry, Palacky University, Hnevotinska 3, Olomouc 775 15, Czech Republic.
Milos MojovicFaculty of Physical Chemistry, University of Belgrade, Studentski trg 12-16, Belgrade, Serbia.
Aleksandra PavicevicFaculty of Physical Chemistry, University of Belgrade, Studentski trg 12-16, Belgrade, Serbia.
Martin KabelacDepartment of Chemistry, Faculty of Science, University of South Bohemia, Branisovska 31, Ceske Budejovice 370 05, Czech Republic.
Bruce A FreemanDepartment of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh PA, 15261, USA.
Michaela PekarovaThe Czech Academy of Sciences, Institute of Biophysics, Kralovopolska 135, Brno 612 65, Czech Republic.
Jan VacekDepartment of Medical Chemistry and Biochemistry, Faculty of Medicine and Dentistry, Palacky University, Hnevotinska 3, Olomouc 775 15, Czech Republic; The Czech Academy of Sciences, Institute of Biophysics, Kralovopolska 135, Brno 612 65, Czech Republic. Electronic address: jan.vacek@upol.cz.
Czech Academy of Sciences, Institute of Biophysics · CZUniversity of Belgrade · RSPalacký University Olomouc · CZUniversity of Pittsburgh · USUniversity of South Bohemia in České Budějovice · CZ

Funding

Vascular Subphenotypes of Lung DiseaseP01HL103455 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GLADWIN, MARK T · 2011 to 2020
$26.1M
Translational Training Program in Pulmonary Biology and MedicineT32HL007563 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Melanie Koenigshoff · 1985 to 2026
$12.3M
Redox-Derived Pulmonary Anti-Inflammatory MediatorsR01HL064937 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI FREEMAN, BRUCE ALAN · 2000 to 2015
$5.6M
Redox Transduction of Nitric Oxide SignalingR37HL058115 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI FREEMAN, BRUCE ALAN · 2008 to 2017
$5.2M
Anti-Inflammatory Lipid Mediators in AsthmaR01HL132550 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI FREEMAN, BRUCE ALAN, HOLGUIN, FERNANDO · 2016 to 2019
$2.9M
NHLBI NIH HHS P01 HL103455NHLBI NIH HHS R01 HL064937NHLBI NIH HHS R01 HL132550NHLBI NIH HHS R37 HL058115NHLBI NIH HHS T32 HL007563
6 · The paper itself

Abstract

Nitro-fatty acids modulate inflammatory and metabolic stress responses, thus displaying potential as new drug candidates. Herein, we evaluate the redox behavior of nitro-oleic acid (NO

Indexed as

Oxidation-ReductionFatty AcidsHumansNitric AcidNitric OxideNitro CompoundsSerum Albumin, HumanFatty AcidsNitric AcidNitric OxideNitro CompoundsSerum Albumin, HumanElectrophilesNitrated fatty acidsNOOleic acidProteinsSerum albumin binding

Identifiers

PMID31170679
PMCPMC6554544
OpenAlexW2944359626

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.