Evidence map›Paper›PMID 31170193›Full record

Trial reportPloS one2019

Estimating the costs of HIV clinic integrated versus non-integrated treatment of pre-cancerous cervical lesions and costs of cervical cancer treatment in Kenya.

Elisabeth L Vodicka, Michael H Chung, Marita R Zimmermann, Rose J Kosgei, Fan Lee, Nelly R Mugo, Timothy C Okech, Samah R Sakr, Andy Stergachis, Louis P Garrison and 1 more

Open access · goldAbstract readClinical Trial
In one paragraph

Trial report in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Elisabeth L VodickaUniversity of Washington, Seattle, Washington, United States of America.ORCID 0000-0002-7370-0919
Michael H ChungUniversity of Washington, Seattle, Washington, United States of America.
Marita R ZimmermannUniversity of Washington, Seattle, Washington, United States of America.
Rose J KosgeiUniversity of Nairobi, Nairobi, Kenya.
Fan LeeUniversity of Washington, Seattle, Washington, United States of America.
Nelly R MugoUniversity of Nairobi, Nairobi, Kenya.
Timothy C OkechUnited States International University, Nairobi, Kenya.
Samah R SakrCoptic Hope Center for Infectious Diseases, Nairobi, Kenya.
Andy StergachisUniversity of Washington, Seattle, Washington, United States of America.
Louis P GarrisonUniversity of Washington, Seattle, Washington, United States of America.
Joseph B BabigumiraUniversity of Washington, Seattle, Washington, United States of America.
University of Washington · USUniversity of Nairobi · KEUnited States International University Africa · KE

Funding

PS09-991, KENYA, COPTIC HOSPITAL/UNIVERSITY OF WASHINGTON COLLABORATIVE HIV-1 CARE PROGRAMU2GPS002047 · PS · COPTIC ORTHODOX CHURCH · PI YOWAKIM, PAUL · 2010 to 2016
$27.7M
NCHHSTP CDC HHS U2G PS002047
6 · The paper itself

Abstract

objectivesTo estimate the modified societal costs of cervical cancer treatment in Kenya; and to compare the modified societal costs of treatment for pre-cancerous cervical lesions integrated into same-day HIV care compared to "non-integrated" treatment when the services are not coordinated on the same day. MATERIALS AND

methodsA micro-costing study was conducted at Coptic Hope Center for Infectious Diseases and Kenyatta National Hospital from July 1-October 31, 2014. Interviews were conducted with 54 patients and 23 staff. Direct medical, non-medical (e.g., overhead), and indirect (e.g., time) costs were calculated for colposcopy, cryotherapy, Loop Electrosurgical Excision Procedure (LEEP), and treatment of cancer. All costs are reported in 2017 US dollars.

resultsPatients had a mean age of 41 and daily earnings of $6; travel time to the facility averaged 2.8 hours. From the modified societal perspective, per-procedure costs of colposcopy were $41 (integrated) vs. $91 (non-integrated). Per-procedure costs of cryotherapy were $22 (integrated) vs. $46 (non-integrated), whereas costs of LEEP were $50 (integrated) and $99 (non-integrated). This represents cost savings of $25 for cryotherapy and $50 for colposcopy and LEEP when provided on the same day as an HIV-care visit. Treatment for cervical cancer cost $1,345-$6,514, depending on stage. Facility-based palliative care cost $59/day.

conclusionsIntegrating treatment of pre-cancerous lesions into HIV care is estimated to be cost-saving from a modified societal perspective. These costs can be applied to financial and economic evaluations in Kenya and similar urban settings in other low-income countries.

Indexed as

Costs and Cost AnalysisHIV-1HIV InfectionsPrecancerous ConditionsUterine Cervical NeoplasmsAdultFemaleHumansKenya

Identifiers

PMID31170193
PMCPMC6553698
OpenAlexW2993126398

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.