Evidence map›Paper›PMID 31170000›Full record

ArticleFASEB journal : official publication of the Federation of American Societies for Experimental Biology2019

SALM4 regulates angiogenic functions in endothelial cells through VEGFR2 phosphorylation at Tyr1175.

Dong Young Kim, Jeong Ae Park, Yeomyung Kim, Minyoung Noh, Songyi Park, Eunkyung Lie, Eunjoon Kim, Young-Myeong Kim, Young-Guen Kwon

Open access · hybridAbstract read
In one paragraph

Article in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Dong Young KimDepartment of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul, South Korea.
Jeong Ae ParkDepartment of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul, South Korea.
Yeomyung KimDepartment of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul, South Korea.
Minyoung NohDepartment of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul, South Korea.
Songyi ParkDepartment of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul, South Korea.
Eunkyung LieDepartment of Biological Sciences, Korea Advanced Institute for Science and Technology, Daejeon, South Korea.
Eunjoon KimDepartment of Biological Sciences, Korea Advanced Institute for Science and Technology, Daejeon, South Korea.
Young-Myeong KimDepartment of Molecular and Cellular Biochemistry, School of Medicine, Kangwon National University, Chuncheon-si, South Korea.
Young-Guen KwonDepartment of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul, South Korea.
Yonsei University · KRKorea Advanced Institute of Science and Technology · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Angiogenesis depends on VEGF-mediated signaling. However, the regulatory mechanisms and functions of individual VEGF receptor 2 (VEGFR2) phosphorylation sites remain unclear. Here, we report that synaptic adhesion-like molecule 4 (SALM4) regulates a specific VEGFR2 phosphorylation site. SALM4 silencing in HUVECs and

Indexed as

Amino Acid SequenceAnimalsCell Adhesion Molecules, NeuronalFetal BloodGene Expression RegulationHumansHuman Umbilical Vein Endothelial CellsLeukocytes, MononuclearMiceMice, KnockoutNeovascularization, PathologicNeovascularization, PhysiologicPhosphorylationRNA, MessengerVascular Endothelial Growth Factor Receptor-2Cell Adhesion Molecules, NeuronalLrfn3 protein, mouseRNA, MessengerVascular Endothelial Growth Factor Receptor-2endothelial leakageischemia reperfusionvascular permeabilityVEGF signaling

Identifiers

PMID31170000
PMCPMC6704462
OpenAlexW2948452292

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.