Evidence map›Paper›PMID 31169858›Full record

ArticleNanoscale2019

Brilliant blue, green, yellow, and red fluorescent diamond particles: synthesis, characterization, and multiplex imaging demonstrations.

Nicholas Nunn, Neeraj Prabhakar, Philipp Reineck, Valentin Magidson, Erina Kamiya, William F Heinz, Marco D Torelli, Jessica Rosenholm, Alexander Zaitsev, Olga Shenderova

Abstract read
In one paragraph

Article in Nanoscale, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Optical and electronic spin properties of fluorescent micro- and nanodiamonds upon prolonged ultrahigh-temperature annealing.Journal of vacuum science and technology. B, Nanotechnology & microelectronics : materials, processing, measurement, & phenomena : JVST B · 2023
    Article
  3. Clot Imaging Using Photostable Nanodiamond.Nanomaterials (Basel, Switzerland) · 2023
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. A Perspective on Fluorescent Nanodiamond Bioimaging.Small (Weinheim an der Bergstrasse, Germany) · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Nicholas NunnAdámas Nanotechnologies, Inc., 8100 Brownleigh Drive, Suite 120, Raleigh, NC 27617, USA. nnunn@adamasnano.com oshenderova@adamasnano.com.
Neeraj Prabhakar
Philipp Reineck
Valentin Magidson
Erina Kamiya
William F Heinz
Marco D Torelli
Jessica Rosenholm
Alexander Zaitsev
Olga Shenderova

Funding

Fluorescent Nanodiamonds for Multiplexed Imaging and DiagnosticsR43CA232901 · NCI · ADAMAS NANOTECHNOLOGIES, INC. · PI BACKER, JOSEPH M, SHENDEROVA, OLGA A · 2018 to 2019
$346k
NCI NIH HHS HHSN261200800001ENCI NIH HHS R43 CA232901NHLBI NIH HHS HHSN268201500010C
6 · The paper itself

Abstract

Until recently, the number of emission colors available from fluorescent diamond particles was primarily limited to red to near-infrared fluorescence from the nitrogen-vacancy color center in type Ib synthetic diamond and green fluorescence associated with the nitrogen-vacancy-nitrogen center in type Ia natural diamond. Using our recently reported rapid thermal annealing technique, we demonstrate the capability of producing fluorescent diamond particles that exhibit distinctive blue, green, yellow, and red fluorescence from the same synthetic diamond starting material. Utilizing these multiple colored diamonds, we analyze their fluorescence characteristics both in-solution as well as on-substrate and additionally evaluate their viability in simple multiplex imaging and cellular bioimaging experiments. While there are still challenges associated with their immediate use in traditional multiplex imaging, this novel approach opens new opportunities to enhance the capability and flexibility of fluorescent diamond particles at the nanoscale.

Identifiers

PMID31169858
PMCPMC6642439

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.