Evidence map›Paper›PMID 31169043›Full record

ArticleJournal of enzyme inhibition and medicinal chemistry2019

Synthesis and characterisation of a new benzamide-containing nitrobenzoxadiazole as a GSTP1-1 inhibitor endowed with high stability to metabolic hydrolysis.

Veronica Di Paolo, Chiara Fulci, Dante Rotili, Francesca Sciarretta, Alessia Lucidi, Blasco Morozzo Della Rocca, Anastasia De Luca, Antonio Rosato, Luigi Quintieri, Anna Maria Caccuri

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of enzyme inhibition and medicinal chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. The Nitrobenzoxadiazole Derivative NBDHEX Behaves asPharmaceuticals (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Veronica Di Paoloa Department of Pharmaceutical and Pharmacological Sciences , University of Padova , Padova , Italy.
Chiara Fulcib Department of Experimental Medicine , "Tor Vergata" University of Rome , Rome , Italy.
Dante Rotilic Department of Drug Chemistry and Technologies , "Sapienza" University of Rome , Rome , Italy.ORCID http://orcid.org/0000-0002-8428-8763
Francesca Sciarrettab Department of Experimental Medicine , "Tor Vergata" University of Rome , Rome , Italy.
Alessia Lucidic Department of Drug Chemistry and Technologies , "Sapienza" University of Rome , Rome , Italy.
Blasco Morozzo Della Roccad Department of Biology , "Tor Vergata" University of Rome , Rome , Italy.
Anastasia De Lucad Department of Biology , "Tor Vergata" University of Rome , Rome , Italy.
Antonio Rosatoe Department of Surgery, Oncology and Gastroenterology , University of Padova , Padova , Italy.ORCID http://orcid.org/0000-0002-5263-8386
Luigi Quintieria Department of Pharmaceutical and Pharmacological Sciences , University of Padova , Padova , Italy.ORCID http://orcid.org/0000-0001-7403-0921
Anna Maria Caccurib Department of Experimental Medicine , "Tor Vergata" University of Rome , Rome , Italy.ORCID http://orcid.org/0000-0002-3756-4163
University of Rome Tor Vergata · ITUniversity of Padua · ITSapienza University of Rome · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The antitumor agent 6-((7-nitrobenzo[

Indexed as

4-Chloro-7-nitrobenzofurazanAntineoplastic AgentsBenzamidesCell Line, TumorCell ProliferationCell SurvivalDose-Response Relationship, DrugDrug Screening Assays, AntitumorEnzyme InhibitorsGlutathione S-Transferase piHumansHydrolysisModels, MolecularMolecular StructureStructure-Activity Relationship4-Chloro-7-nitrobenzofurazanAntineoplastic AgentsbenzamideBenzamidesEnzyme InhibitorsGlutathione S-Transferase piA375 human melanomaglutathioneGSTP1-1NitrobenzoxadiazolesTRAF2

Identifiers

PMID31169043
PMCPMC6566875
OpenAlexW2950291897

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.