ArticleAnnals of the New York Academy of Sciences2019
Weighing the risks of high intakes of selected micronutrients compared with the risks of deficiencies.
Article in Annals of the New York Academy of Sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- Diversified food fortification portfolios can enhance coverage of micronutrient-vulnerable populations in West Africa.Nature food · 2026Article
- Impact of large-scale food fortification programmes on micronutrient inadequacies and their implementation costs: a modelling analysis.The Lancet. Global health · 2026Article
- The Cost and Cost-Effectiveness of Vitamin A Supplementation: An Assessment of a Vitamin A Days-Plus Event in Burkina Faso.Food and nutrition bulletin · 2025Article
- Simulated Impact of Vitamin A-Fortified Sugar on Dietary Adequacy and Association of Usual Sugar Intake With Plasma and Breast Milk Retinol Among Lactating Zambian Women.Maternal & child nutrition · 2025Article
- Biological, dietetic and pharmacological properties of vitamin BNPJ science of food · 2025Review
- Digital tools and technologies used in food fortification: A scoping review.Annals of the New York Academy of Sciences · 2025Article
- The Potential for Bouillon Fortification to Reduce Dietary Micronutrient Inadequacy: Modeling Analyses Using National Survey Data from Cameroon, Ghana, and Haiti.Current developments in nutrition · 2024Article
- The Policy of Compulsory Large-Scale Food Fortification in Sub-Saharan Africa.Foods (Basel, Switzerland) · 2024Review
- Current and potential contributions of large-scale food fortification to meeting micronutrient requirements in Senegal: a modelling study using household food consumption data.BMJ public health · 2024Article
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- Dietary supplements, guideline alignment and biochemical nutrient status in pregnancy: Findings from the Queensland Family Cohort pilot study.Maternal & child nutrition · 2024Observational
- Is Dietary (Food) Supplement Intake Reported in European National Nutrition Surveys?Nutrients · 2023Review
- Micronutrient intakes in the Dutch diet: foods, fortified foods and supplements in a cross sectional study.European journal of nutrition · 2023Article
- Dietary supplements increase the risk of excessive micronutrient intakes in Danish children.European journal of nutrition · 2023Article
- Effects of Oral Nutritional Supplementation on Patients with Venous Ulcers: A Clinical Trial.Journal of clinical medicine · 2022Article
- Decisions to Start, Strengthen, and Sustain Food Fortification Programs: An Application of the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) Evidence to Decision (EtD) Framework in Nigeria.Current developments in nutrition · 2022Article
- Do Multivitamin/Mineral Dietary Supplements for Young Children Fill Critical Nutrient Gaps?Journal of the Academy of Nutrition and Dietetics · 2022Article
- The Role of Multiply-Fortified Table Salt and Bouillon in Food Systems Transformation.Nutrients · 2022Article
- Review
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
Several intervention strategies are available to reduce micronutrient deficiencies, but uncoordinated implementation of multiple interventions may result in excessive intakes. We reviewed relevant data collection instruments and available information on excessive intakes for selected micronutrients and considered possible approaches for weighing competing risks of intake above tolerable upper intake levels (ULs) versus insufficient intakes at the population level. In general, population-based surveys in low- and middle-income countries suggest that dietary intakes greater than the UL are uncommon, but simulations indicate that fortification and supplementation programs could lead to high intakes under certain scenarios. The risk of excessive intakes can be reduced by considering baseline information on dietary intakes and voluntary supplement use and continuously monitoring program coverage. We describe a framework for comparing risks of micronutrient deficiency and excess, recognizing that critical information for judging these risks is often unavailable. We recommend (1) assessing total dietary intakes and nutritional status; (2) incorporating rapid screening tools for routine monitoring and surveillance; (3) addressing critical research needs, including evaluations of the current ULs, improving biomarkers of excess, and developing methods for predicting and comparing risks and benefits; and (4) ensuring that relevant information is used in decision-making processes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.