Evidence map›Paper›PMID 31168658›Full record

ReviewCurrent diabetes reports2019

Circadian Clock Genes in Diabetic Kidney Disease (DKD).

Olanrewaju A Olaoye, Sarah H Masten, Rajesh Mohandas, Michelle L Gumz

Open access · greenAbstract readReview
In one paragraph

Review in Current diabetes reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.7field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Review
  5. Irbesartan ameliorates diabetic kidney injury inJournal of translational internal medicine · 2024
    Article
  6. Article
  7. Clock genes rescue nphp mutations in zebrafish.Human molecular genetics · 2022
    Article
  8. Article
  9. Postprandial effects on electrolyte homeostasis in the kidney.American journal of physiology. Renal physiology · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Olanrewaju A OlaoyeDepartment of Medicine, Division of Nephrology, Hypertension, and Renal Transplantation, University of Florida, 1600 SW Archer Road, Box 100224, Gainesville, FL, 32610, USA.
Sarah H MastenDepartment of Medicine, Division of Nephrology, Hypertension, and Renal Transplantation, University of Florida, 1600 SW Archer Road, Box 100224, Gainesville, FL, 32610, USA.
Rajesh MohandasDepartment of Medicine, Division of Nephrology, Hypertension, and Renal Transplantation, University of Florida, 1600 SW Archer Road, Box 100224, Gainesville, FL, 32610, USA.
Michelle L GumzDepartment of Medicine, Division of Nephrology, Hypertension, and Renal Transplantation, University of Florida, 1600 SW Archer Road, Box 100224, Gainesville, FL, 32610, USA. Michelle.Gumz@medicine.ufl.edu.
University of Florida · USNorth Florida/South Georgia Veterans Health System · US

Funding

Per1 and the kidney clock in hypertensionR01DK109570 · NIDDK · UNIVERSITY OF FLORIDA · PI GUMZ, MICHELLE L · 2017 to 2021
$1.5M
NCATS NIH HHS L30 TR001247NIDDK NIH HHS L30 DK096643NIDDK NIH HHS R01 DK109570
6 · The paper itself

Abstract

purpose of reviewThe purpose of this review is to provide a brief summary about the current state of knowledge regarding the circadian rhythm in the regulation of normal renal function. RECENT

findingsThere is a lack of information regarding how the circadian clock mechanisms may contribute to the development of diabetic kidney disease. We discuss recent findings regarding mechanisms that are established in diabetic kidney disease and are known to be linked to the circadian clock as possible connections between these two areas. Here, we hypothesize various mechanisms that may provide a link between the clock mechanism and kidney disease in diabetes based on available data from humans and rodent models.

Indexed as

Circadian ClocksDiabetes MellitusDiabetic NephropathiesCircadian RhythmHumansKidneyBMAL1Circadian rhythmHIFRenal functionShift work

Identifiers

PMID31168658
PMCPMC7223054
OpenAlexW2954983483

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.