Evidence map›Paper›PMID 31168497›Full record

ArticleEpilepsia open2019

Clinical features and treatment outcomes of Juvenile myoclonic epilepsy patients.

Yingying Zhang, Jiani Chen, Jiechuan Ren, Wenyu Liu, Tianhua Yang, Dong Zhou

Abstract read
In one paragraph

Article in Epilepsia open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yingying ZhangDepartment of Neurology West China Hospital Sichuan University Chengdu China.
Jiani ChenDepartment of Neurology West China Hospital Sichuan University Chengdu China.
Jiechuan RenDepartment of Neurology Beijing Tiantan Hospital Capital Medical University Beijing China.
Wenyu LiuDepartment of Neurology West China Hospital Sichuan University Chengdu China.
Tianhua YangDepartment of Neurology West China Hospital Sichuan University Chengdu China.
Dong ZhouDepartment of Neurology West China Hospital Sichuan University Chengdu China.ORCID https://orcid.org/0000-0001-7101-4125

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aim of this study was to evaluate the clinical features and treatment outcomes of patients with juvenile myoclonic epilepsy (JME) in western China.

methodWe continuously reviewed one hundred and five outpatients with JME who were diagnosed and treated at the Epilepsy Registration Center of West China Hospital between October 2012 and July 2014. Seizure control stratified into different seizure types and by antiepileptic drugs (AEDs) was prospectively evaluated every 3-6 months.

resultsAmong 105 patients with JME, eighty-five patients (81%) received monotherapy including valproate (VPA, 47%) and levetiracetam (LEV, 43%) treatment. The rates of seizure freedom 1, 3, and 5 years after the initiation of AED treatment were 64.8% (68/105), 29.5% (31/105), and 14.6% (12/82) in JME patients, respectively. Patients with myoclonic seizure (MS) and absence seizure (AS) were less frequently seizure-free than those with MS and generalized tonic-clonic seizure (GTCS) ( SIGNIFICANCE: Our data suggest that in JME, seizure control is linked to seizure type, possibly allowing a more individualized approach when counseling JME patients.

Indexed as

juvenile myoclonic epilepsylevetiracetamseizure outcomevalproate

Identifiers

PMID31168497
PMCPMC6546016

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.