Evidence map›Paper›PMID 31168483›Full record

ArticleWellcome open research2019

A seven-year study on the effect of the pre-erythrocytic malaria vaccine candidate RTS,S/AS01

Francis M Ndungu, Jedida Mwacharo, Juliana Wambua, Patricia Njuguna, Kevin Marsh, Chris Drakeley, Philip Bejon

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Wellcome open research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Iron Deficiency Is Associated With Reduced Levels of Plasmodium falciparum-specific Antibodies in African Children.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Vaccines · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 4 countries.

Francis M NdunguDepartment of Biosciences, KEMRI/Wellcome Trust Research Programme, Kilifi, 80108, Kenya.ORCID https://orcid.org/0000-0002-8977-0030
Jedida MwacharoDepartment of Biosciences, KEMRI/Wellcome Trust Research Programme, Kilifi, 80108, Kenya.
Juliana WambuaDepartment of Biosciences, KEMRI/Wellcome Trust Research Programme, Kilifi, 80108, Kenya.
Patricia NjugunaDepartment of Biosciences, KEMRI/Wellcome Trust Research Programme, Kilifi, 80108, Kenya.
Kevin MarshDepartment of Biosciences, KEMRI/Wellcome Trust Research Programme, Kilifi, 80108, Kenya.ORCID https://orcid.org/0000-0001-8377-5466
Chris DrakeleyInfection & Immunity Department, London School of Hygiene & Tropical Medicine, London, WC1E 7HT, UK.ORCID https://orcid.org/0000-0003-4863-075X
Philip BejonInfection & Immunity Department, London School of Hygiene & Tropical Medicine, London, WC1E 7HT, UK.ORCID https://orcid.org/0000-0002-2135-7549
Malawi University of Science and Technology · MWLondon School of Hygiene & Tropical Medicine · GB

Funding

Medical Research Council MR/P020321/1Wellcome Trust
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

blood stagesimmunitymalariaPlasmodium falciparumpre-erythrocyticRTSS/AS01 EVaccines

Identifiers

PMID31168483
PMCPMC6545824
OpenAlexW2919101207

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.