Evidence map›Paper›PMID 31168407›Full record

ArticleRMD open2019

Impact of autoimmune rheumatic diseases on birth outcomes: a population-based study.

Jennifer Strouse, Brittney M Donovan, Munazza Fatima, Ruth Fernandez-Ruiz, Rebecca J Baer, Nichole Nidey, Chelsey Forbess, Gretchen Bandoli, Randi Paynter, Nisha Parikh and 3 more

Erratum issuedOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in RMD open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 20 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 6 pooled it
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 6 syntheses or guidelines pooled it, 47 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 8 institutions in 1 country.

Jennifer StrouseInternal Medicine, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA.
Brittney M DonovanInternal Medicine, Vanderbilty University Medical Center, Iowa City, Iowa, USA.
Munazza FatimaInternal Medicine, Iowa City VA Medical Center, Iowa City, Iowa, USA.
Ruth Fernandez-RuizInternal Medicine, NYU Langone Health, New York, New York, USA.
Rebecca J BaerPediatrics, University of California San Diego Health System, San Diego, California, USA.
Nichole NideyEpidemiology, University of Iowa, Iowa City, Iowa, USA.
Chelsey ForbessInternal Medicine, Harbor-UCLA Medical Center, Torrance, California, USA.
Gretchen BandoliPediatrics, University of California San Diego Health System, San Diego, California, USA.
Randi PaynterEpidemiology and Biostatistics, University of California San Francisco School of Medicine, San Francisco, California, USA.
Nisha ParikhInternal Medicine, Div of Cardiology, University of California San Francisco School of Medicine, San Francisco, California, USA.
Laura Jeliffe-PawlowskiEpidemiology and Biostatistics, University of California San Francisco School of Medicine, San Francisco, California, USA.
Kelli K RyckmanEpidemiology, University of Iowa, Iowa City, Iowa, USA.
Namrata SinghRheumatology, Iowa City VA Medical Center, Iowa City, Iowa, USA.ORCID 0000-0001-7149-363X
University of California, San Francisco · USUC San Diego Health System · USUniversity of Iowa · USUniversity of Iowa Hospitals and Clinics · USIowa City VA Medical Center · USNYU Langone Health · USUCLA Medical Center · USVanderbilt University Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Autoimmune rheumatic diseases (ARDs) affect women of childbearing age and have been associated with adverse birth outcomes. The impact of diseases like ankylosing spondylitis and psoriatic arthritis (PsA) on birth outcomes remains less studied to date. Our objective was to evaluate the impact of ARDs on preterm birth (PTB), congenital anomalies, low birth weight (LBW) and small for gestational age (SGA), in a large cohort of women. Methods: We conducted a propensity score-matched analysis to predict ARD from a retrospective birth cohort of all live, singleton births in California occurring between 2007 and 2012. Data were derived from birth certificate records linked to hospital discharge International Classification of Diseases, ninth revision codes. Results: We matched 10 244 women with a recorded ARD diagnosis (rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), antiphospholipid syndrome, PsA); ankylosing spondylitis and juvenile idiopathic arthritis (JIA) to those without an ARD diagnosis. The adjusted OR (aOR) of PTB was increased for women with any ARD (aOR 1.93, 95% CI 1.78 to 2.10) and remained significant for those with RA, SLE, PsA and JIA. The odds of LBW and SGA were also significantly increased among women with an ARD diagnosis. ARDs were not associated with increased odds of congenital anomalies. Conclusion: Consistent with prior literature, we found that women with ARDs are more likely to have PTB or deliver an SGA infant. Some reassurance is provided that an increase in congenital anomalies was not found even in this large cohort.

Indexed as

autoimmune rheumatic diseasespreterm birthsmall for gestational age

Identifiers

PMID31168407
PMCPMC6525602
OpenAlexW2937874616

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.