Evidence map›Paper›PMID 31168380›Full record

ArticleOpen heart

Association of income and health-related quality of life in atrial fibrillation.

Emily Guhl, Andrew Althouse, Michael Sharbaugh, Alexandra M Pusateri, Michael Paasche-Orlow, Jared W Magnani

Abstract read
In one paragraph

Article in Open heart. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Global burden of atrial fibrillation/atrial flutter and its attributable risk factors from 1990 to 2021.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Social determinants of atrial fibrillation.Nature reviews. Cardiology · 2021
    Review
  15. Article
  16. Association of patient-reported outcomes with hospitalization risk in atrial fibrillation.American heart journal plus : cardiology research and practice · 2021
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Emily GuhlHeart and Vascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.ORCID 0000-0002-9153-6016
Andrew AlthouseHeart and Vascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
Michael SharbaughHeart and Vascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
Alexandra M PusateriDepartment of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Michael Paasche-OrlowDepartment of Medicine, Boston University School of Medicine, Boston, Massachusetts, USA.
Jared W MagnaniHeart and Vascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.

Funding

Diversity Supplement for geocoding in the parent grant "A Mobile Relational Agent to Enhance Atrial Fibrillation self-care"R33HL144669 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MAGNANI, JARED W. · 2020 to 2023
$3.8M
Mobile Health intervention for rural atrial fibrillationR01HL143010 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MAGNANI, JARED W. · 2019 to 2022
$3.0M
A Mobile Relational Agent to Enhance Atrial Fibrillation Self-careR61HL144669 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MAGNANI, JARED W. · 2019 to 2019
$766k
Doris Duke Charitable Foundation 2015084NHLBI NIH HHS R01 HL143010NHLBI NIH HHS R33 HL144669NHLBI NIH HHS R61 HL144669
6 · The paper itself

Abstract

Objective: Health-related quality of life (HRQoL) is a patient-centred benchmark promoted by clinical guidelines in atrial fibrillation (AF). Income is associated with health outcomes, but how income effects HRQoL in AF has limited investigation. Methods: We enrolled a convenience cohort with AF receiving care at a regional healthcare system and assessed demographics, medical history, AF treatment, income, education and health literacy. We defined income as a categorical variable (<$20 000; $20 000-$49 999; $50 000-$99 999; >$100 000). We used two complementary HRQoL measures: (1) the atrial fibrillation effect on quality of life (AFEQT), measuring composite and domain scores (daily activity, symptoms, treatment concerns, treatment satisfaction; range 0-100); (2) the 12-item Short Form Survey (SF-12), measuring general HRQoL with physical and mental health domains (range 0-100). We related income to HRQoL and adjusted for relevant covariates. Results: In 295 individuals with AF (age 71±10, 40% women), we observed significant differences in HRQoL by income. Higher mean composite AFEQT scores were observed for higher income groups: participants with income <$20 000 had the lowest HRQoL (n=35, 68.2±21.4), and those with income >$100 000 had the highest HRQoL (n=64, 81.9±17.0; p=0.04). We also observed a significant difference by income in the AFEQT daily activity domain (p=0.02). Lower income was also associated with lower HRQoL in the mental health composite score of the SF-12 (59.7±21.5, income <$20 000 vs 79.3±16.3, income >$100 000; p<0.01). Conclusion: We determined that income was associated with HRQoL in a cohort with prevalent AF. Given the marked differences, we consider income as essential for understanding patient-centred outcomes in AF.

Indexed as

atrial fibrillationepidemiologypublic health

Identifiers

PMID31168380
PMCPMC6519582

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.