ArticleAllergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology2019
Variants in the IL17 pathway genes are associated with atopic asthma and atopy makers in a South American population.
Article in Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 27 citations in OpenAlex.
- Exploring Oxygen Therapy as a Supporting Treatment for Asthma: Current Insights and Perspectives.International journal of molecular sciences · 2025Review
- Alternative Combinations of IL17A Polymorphic Variants with the Variants of TNF, IL1B, IL6, and IL8 Proinflammatory Cytokines Genes in Uterine Leiomyoma.Bulletin of experimental biology and medicine · 2025Article
- HMGB1/RAGE Signaling Regulates Th17/IL-17 and Its Role in Bronchial Epithelial-Mesenchymal Transformation.Current molecular medicine · 2024Article
- Genetic variants associated with SARS-CoV-2 infection also affect lung function and asthma severity.Heliyon · 2023Article
- Understanding and controlling asthma in Latin America: A review of recent research informed by the SCAALA programme.Clinical and translational allergy · 2023Review
- Mechanisms of Corticosteroid Resistance in Type 17 Asthma.Journal of immunology (Baltimore, Md. : 1950) · 2022Article
- NFκB1 Polymorphisms Are Associated with Severe Influenza A (H1N1) Virus Infection in a Canadian Population.Microorganisms · 2022Article
- Drug rash with eosinophilia and systemic symptoms syndrome masquerading as a lymphoproliferative disorder in a young adult on immunosuppressive therapy for rheumatoid arthritis: a case report.Journal of medical case reports · 2022Article
- Review
- An update on the diagnostic biomarkers for asthma.Journal of family medicine and primary care · 2021Review
- Treatment options in type-2 low asthma.The European respiratory journal · 2021Review
- mRNA expression analysis of interleukins 17A and 17F in bronchial asthmatic patients from Northern Indian population.Journal of family medicine and primary care · 2020Article
- The role of interleukin-17 in asthma: a protective response?ERJ open research · 2020Review
- Regulation of γδT17 cells by Mycobacterium vaccae through interference with Notch/Jagged1 signaling pathway.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2020Article
- Homoharringtonine Inhibits Allergic Inflammations by Regulating NF-κB-miR-183-5p-BTG1 Axis.Frontiers in pharmacology · 2020Article
- Kawasaki Disease and Allergic Diseases.Frontiers in pediatrics · 2020Review
- Sputum IL-26 Is Overexpressed in Severe Asthma and Induces Proinflammatory Cytokine Production and Th17 Cell Generation: A Case-Control Study of Women.Journal of asthma and allergy · 2020Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAsthma is a complex disorder with multiple phenotypes which can influence its severity and response to treatment. The T MATERIALS AND
methodsGenotyping was performed using a commercial panel in 1245 participants of SCAALA cohort. The study included 91 SNVs in IL-17 pathway genes. Logistic regressions for asthma and atopy markers were performed using PLINK 1.9. In silico analyses were performed using rSNPbase, RegulomeDB, and Gtex portal for in silico gene expression. RESULTS AND DISCUSSION: The T allele of rs1974226 in
conclusionThe genetic variants in IL-17-related genes are associated with the atopic asthma phenotype and IgE production.
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