Evidence map›Paper›PMID 31167949›Full record

ArticlemSphere2019

Screening Mycobacterium tuberculosis Secreted Proteins Identifies Mpt64 as a Eukaryotic Membrane-Binding Bacterial Effector.

Chelsea E Stamm, Breanna L Pasko, Sujittra Chaisavaneeyakorn, Luis H Franco, Vidhya R Nair, Bethany A Weigele, Neal M Alto, Michael U Shiloh

Open access · goldAbstract read
In one paragraph

Article in mSphere, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 41 citations in OpenAlex.

  1. Review
  2. TheFrontiers in medicine · 2026
    Article
  3. Recent Characterization of Key Proteins to Combat Tuberculosis.Advances in experimental medicine and biology · 2026
    Review
  4. Review
  5. Article
  6. Review
  7. SMURF2 inhibits autophagic control ofbioRxiv : the preprint server for biology · 2025
    Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Frontiers in immunology · 2024
    Article
  16. Article
  17. Review
  18. Autophagy, cell death, and cytokines inEmerging microbes & infections · 2023
    Review
  19. Frontiers in immunology · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Chelsea E StammDepartment of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA.ORCID 0000-0003-4957-6070
Breanna L PaskoDepartment of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Sujittra ChaisavaneeyakornDepartment of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Luis H FrancoDepartment of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Vidhya R NairDepartment of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Bethany A WeigeleDepartment of Microbiology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Neal M AltoDepartment of Microbiology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.ORCID 0000-0002-7602-3853
Michael U ShilohDepartment of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA michael.shiloh@utsouthwestern.edu.ORCID 0000-0003-4329-2253
The University of Texas Southwestern Medical Center · US

Funding

RP5: Chemical proteomic discovery of small-molecule probes for autophagy proteinsU19AI142784 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI CRAVATT, BENJAMIN F · 2019 to 2023
$36.9M
MOLECULAR MICROBIOLOGY TRAINING GRANTT32AI007520 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI Julie K Pfeiffer · 1997 to 2026
$7.0M
Type III effector regulation of host signal transduction systemsR01AI083359 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI ALTO, NEAL MATHEW · 2009 to 2024
$6.3M
Human airway microfold cells in mucosal immunity to bacterial pathogensU01AI125939 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI SHILOH, MICHAEL · 2016 to 2020
$2.2M
Carbon monoxide resistance in Mycobacterium tuberculosis pathogenesisR01AI099439 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI SHILOH, MICHAEL · 2012 to 2016
$2.0M
Type III effector regulation of host GTPase signalingR56AI083359 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI ALTO, NEAL MATHEW · 2014 to 2014
$452k
Identification of novel M. tuberculosis secreted effector proteinsR21AI111023 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI SHILOH, MICHAEL · 2014 to 2015
$430k
NIAID NIH HHS R01 AI083359NIAID NIH HHS R01 AI099439NIAID NIH HHS R21 AI111023NIAID NIH HHS R56 AI083359NIAID NIH HHS T32 AI007520NIAID NIH HHS U01 AI125939NIAID NIH HHS U19 AI142784
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Host-Pathogen InteractionsAnimalsAntigens, BacterialBacterial ProteinsCell MembraneCells, CulturedEndoplasmic ReticulumFemaleHeLa CellsHumansMacrophagesMiceMice, Inbred BALB CMycobacterium tuberculosisRAW 264.7 CellsTuberculosisAntigens, BacterialBacterial ProteinsMPB64 protein, MycobacteriumVirulence Factorseffector functionsMycobacterium tuberculosispathogenesis

Identifiers

PMID31167949
PMCPMC6553557
OpenAlexW2948414188

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.