ArticleScience translational medicine2019
Naturally acquired immunity against immature
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Article in Science translational medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
5.8field-weighted citation impact, top 4% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 49 citations in OpenAlex.
- Elevated Plasmodium falciparum sexual conversion in HbAC and HbAS red blood cells in naturally infected malaria patients.PLoS pathogens · 2026Article
- The transmission-blocking dynamics of Plasmodium falciparum sexual-stage antibody responses in a six-year cohort of Ugandan children and adults.Nature communications · 2026Article
- Host macrophages/monocytes promote malaria transmission by modulating mosquito microbiota via SR-A-mediated phagocytosis.Nature communications · 2026Article
- Asymptomatic school-age children carry the majority of transmissible Plasmodium falciparum infections.Communications medicine · 2026Article
- The kinetics and transmission-blocking dynamics ofResearch square · 2026Article
- Article
- Overview of the host immune response toJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2025Review
- Host complement C3 promotes malaria transmission by killing symbiotic bacteria in the mosquito midgut.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Reversible host cell surface remodelling limits immune recognition and maximizes survival of Plasmodium falciparum gametocytes.PLoS pathogens · 2025Article
- The type 2 immune response in gut homeostasis and parasite transmission in malaria.Trends in parasitology · 2025Review
- The global transcriptome ofMicrobiology spectrum · 2023Article
- Transcriptomic approaches for identifying potential transmission blocking vaccine candidates in3 Biotech · 2023Review
- Anti-Gametocyte Antigen Humoral Immunity and Gametocytemia During Treatment of Uncomplicated Falciparum Malaria: A Multi-National Study.Frontiers in cellular and infection microbiology · 2022Article
- The acquisition of humoral immune responses targetingFrontiers in immunology · 2022Article
- The role of different components of the immune system against Plasmodium falciparum malaria: Possible contribution towards malaria vaccine development.Molecular and biochemical parasitology · 2021Review
- Review
- Antibody signatures of asymptomatic Plasmodium falciparum malaria infections measured from dried blood spots.Malaria journal · 2021Article
- Article
- Plasmodium falciparum Gametocyte Density and Infectivity in Peripheral Blood and Skin Tissue of Naturally Infected Parasite Carriers in Burkina Faso.The Journal of infectious diseases · 2021Article
- Higher gametocyte production and mosquito infectivity in chronic compared to incident Plasmodium falciparum infections.Nature communications · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
31 authors at 11 institutions in 5 countries.
Kathleen W DantzlerDepartment of Immunology and Infectious Disease, Harvard T.H. Chan School of Public Health, Boston, MA, USA.ORCID 0000-0002-6548-7513
Siyuan MaDepartment of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Priscilla NgothoWellcome Centre for Molecular Parasitology, Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, UK.ORCID 0000-0003-3140-5847
Will J R StoneRadboud Institute for Health Sciences, Radboud University Medical Center, Netherlands.
Dingyin TaoW. Harry Feinstone Department of Molecular Microbiology and Immunology and the Malaria Research Institute, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.ORCID 0000-0001-6531-2740
Sanna RijpmaRadboud Institute for Health Sciences, Radboud University Medical Center, Netherlands.ORCID 0000-0002-1593-424X
Mariana De NizWellcome Centre for Molecular Parasitology, Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, UK.
Sandra K Nilsson BarkDepartment of Immunology and Infectious Disease, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Matthijs M JoreRadboud Institute for Health Sciences, Radboud University Medical Center, Netherlands.
Tonke K RaaijmakersRadboud Institute for Health Sciences, Radboud University Medical Center, Netherlands.
Angela M EarlyBroad Institute of Harvard and MIT, Cambridge, MA, USA.
Ceereena Ubaida-MohienNational Institute on Aging, National Institutes of Health, Baltimore, MD, USA.
Leandro LemgruberWellcome Centre for Molecular Parasitology, Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, UK.ORCID 0000-0003-2832-6806
Joseph J CampoAntigen Discovery Inc., Irvine, CA, USA.ORCID 0000-0002-8652-0917
Andy A TengAntigen Discovery Inc., Irvine, CA, USA.
Timothy Q LeAntigen Discovery Inc., Irvine, CA, USA.ORCID 0000-0002-9134-0152
Cassidy L WalkerAntigen Discovery Inc., Irvine, CA, USA.
Patricia HermandSorbonne Universités, UPMC Univ Paris 06, INSERM, Centre d'Immunologie et des Maladies Infectieuses (CIMI-Paris), UMR 1135, ERL CNRS 8255, F-75013 Paris, France.
Philippe DeterreSorbonne Universités, UPMC Univ Paris 06, INSERM, Centre d'Immunologie et des Maladies Infectieuses (CIMI-Paris), UMR 1135, ERL CNRS 8255, F-75013 Paris, France.ORCID 0000-0001-9303-0791
D Huw DaviesDivision of Infectious Diseases, Department of Medicine, University of California, Irvine, CA, USA.
Phil FelgnerDivision of Infectious Diseases, Department of Medicine, University of California, Irvine, CA, USA.
Isabelle MorlaisUMR MIVEGEC UM1-CNRS 5290-IRD 224, Institut de Recherche pour le Développement, Montpellier Cedex, France.ORCID 0000-0002-2962-7670
Dyann F WirthDepartment of Immunology and Infectious Disease, Harvard T.H. Chan School of Public Health, Boston, MA, USA.ORCID 0000-0002-8604-4455
Daniel E NeafseyBroad Institute of Harvard and MIT, Cambridge, MA, USA.
Rhoel R DinglasanW. Harry Feinstone Department of Molecular Microbiology and Immunology and the Malaria Research Institute, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.ORCID 0000-0001-5433-8179
Miriam LauferDivision of Malaria Research, Institute for Global Health, University of Maryland School of Medicine, Baltimore, MD, USA.ORCID 0000-0001-8300-9593
Curtis HuttenhowerDepartment of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA.ORCID 0000-0002-1110-0096
Karl SeydelDepartment of Osteopathic Medical Specialties, College of Osteopathic Medicine, Michigan State University, East Lansing, MI, USA.ORCID 0000-0001-9859-9549
Terrie TaylorDepartment of Osteopathic Medical Specialties, College of Osteopathic Medicine, Michigan State University, East Lansing, MI, USA.
Teun BousemaRadboud Institute for Health Sciences, Radboud University Medical Center, Netherlands. teun.bousema@radboudumc.nl matthias.marti@glasgow.ac.uk.ORCID 0000-0003-2666-094X
Matthias MartiDepartment of Immunology and Infectious Disease, Harvard T.H. Chan School of Public Health, Boston, MA, USA. teun.bousema@radboudumc.nl matthias.marti@glasgow.ac.uk.
Harvard University · USRadboud University Nijmegen · NLAntigen Discovery (United States) · USCentre National de la Recherche Scientifique · FRWellcome Centre for Molecular Parasitology · GBBroad Institute · USNational Institutes of Health · USUniversity of California, Irvine · USUniversity of Malawi · MWJohns Hopkins University · USUniversity of Maryland, Baltimore · US
Funding
The role of monocytes in the pathology of severe malaria.U19AI089683 · NIAID · MICHIGAN STATE UNIVERSITY · PI TAYLOR, TERRIE ELLEN · 2010 to 2023
$21.4MTransmissionU19AI089686 · NIAID · CASE WESTERN RESERVE UNIVERSITY · PI ZIMMERMAN, PETER A. · 2010 to 2016
$9.9MPredicting naturally acquired humoral immunity against malariaR01AI095916 · NIAID · UNIVERSITY OF CALIFORNIA-IRVINE · PI FELGNER, PHILIP LOUIS · 2012 to 2016
$2.1MCytoadherence and sequestration in malaria transmission stagesR01AI077558 · NIAID · HARVARD SCHOOL OF PUBLIC HEALTH · PI MARTI, MATTHIAS · 2010 to 2013
$1.6MEuropean Research Council 639776European Research Council 682360Intramural NIH HHS Z99 AG999999NIAID NIH HHS R01 AI077558NIAID NIH HHS R01 AI095916NIAID NIH HHS U19 AI089683NIAID NIH HHS U19 AI089686Swiss National Science Foundation 165396Wellcome Trust 104111
Abstract
The recent decline in global malaria burden has stimulated efforts toward
Indexed as
AnimalsAntibodies, ProtozoanAntigens, ProtozoanErythrocytesFlow CytometryHumansImmunoblottingMalariaMalaria, FalciparumMiceMicroscopy, FluorescencePhagocytosisPlasmodium falciparumProtozoan ProteinsTandem Mass SpectrometryAntibodies, ProtozoanAntigens, ProtozoanProtozoan Proteins
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.