Evidence map›Paper›PMID 31167857›Full record

ArticleBMJ open2019

Maternal Immunization and Antenatal Care Situation Analysis (MIACSA) study protocol: a multiregional, cross-sectional analysis of maternal immunization delivery strategies to reduce maternal and neonatal morbidity and mortality.

Nathalie Roos, Philipp Lambach, Carsten Mantel, Elizabeth Mason, Flor M Muñoz, Michelle Giles, Allisyn Moran, Joachim Hombach, Theresa Diaz, MIACSA expert advisory panel group

Open access · goldAbstract readClinical Trial Protocol
In one paragraph

Article in BMJ open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Vertical Transmission of Group BInternational journal of microbiology · 2024
    Article
  3. Review
  4. Maternal immunization country readiness: a checklist approach.Human vaccines & immunotherapeutics · 2020
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 5 countries.

Nathalie RoosDepartment of Maternal Newborn Child and Adolescent Health (MCA), Epidemiology Monitoring and Evaluation (EME), World Health Organization, Geneva, Switzerland.
Philipp LambachDepartment of Immunization, Vaccines and Biologicals (IVB), Initiative for Vaccine Research (IVR), World Health Organization, Geneva, Switzerland.
Carsten MantelIndependant consulting and advisory group, MMGH Consulting GmbH, Zürich, Switzerland.
Elizabeth MasonFaculty of epidemiology and population health, Department of infectious disease epidemiology, London School of Hygiene and Tropical Medicine, London, UK.
Flor M MuñozDepartment of Pediatrics, Section of Infectious Diseases, Baylor College of Medicine, Houston, Texas, USA.
Michelle GilesDepartment of Obstetrics and Gynaecology, Monash University and Monash Health, Melbourne, Australia.
Allisyn MoranDepartment of Maternal Newborn Child and Adolescent Health (MCA), Epidemiology Monitoring and Evaluation (EME), World Health Organization, Geneva, Switzerland.
Joachim HombachDepartment of Immunization, Vaccines and Biologicals (IVB), Initiative for Vaccine Research (IVR), World Health Organization, Geneva, Switzerland.
Theresa DiazDepartment of Maternal Newborn Child and Adolescent Health (MCA), Epidemiology Monitoring and Evaluation (EME), World Health Organization, Geneva, Switzerland.
MIACSA expert advisory panel group
World Health Organization · CHBaylor College of Medicine · USLondon School of Hygiene & Tropical Medicine · GBMonash Health · AURobert Koch Institute · DE

Funding

World Health Organization 001
6 · The paper itself

Abstract

introductionMaternal immunization (MI) with tetanus toxoid containing vaccine, is a safe and cost-effective way of preventing neonatal tetanus. Given the prospect of introducing new maternal vaccines in the near future, it is essential to identify and understand current policies, practices and unmet needs for introducing and/or scaling up MI in low-income and middle-income countries (LMICs). METHODS AND ANALYSIS: The Maternal Immunization and Antenatal Care Situation Analysis (MIACSA) is a mixed methods, cross-sectional study that will collect data in four phases: (1) a review of global databases for selected health indicators in 136 LMICs; (2) a structured online survey directed at Maternal, Newborn and Child Health and Expanded Programme on Immunization focal points in all 136 LMICs; (3) semistructured telephone interviews of 30 selected LMICs and (4) 10 week-long country visits, including key informant interviews, health facility visits and focus group discussions. The principal analyses will assess correlations between the various aspects of MI delivery strategies and proxy measures of health systems performance related to vaccine-preventable disease control. The primary outcome will be a typology of existing MI delivery models, and secondary outcomes will include country profiles of child and maternal health indicators, and a MI gaps and needs analysis. ETHICS AND DISSEMINATION: The protocol was approved by the WHO Ethics Review Committee (ERC.0002908). The results will be made available in a project report and submitted for publication in peer-reviewed journals that will be shared broadly among global health decision-makers, researchers, product developers and country-level stakeholders.

Indexed as

ImmunizationPregnancy Complications, InfectiousPrenatal CareTetanusTetanus ToxinClinical Studies as TopicCross-Sectional StudiesFemaleHumansInfantInfant MortalityMaternal MortalityMulticenter Studies as TopicNeurotoxinsPerinatal MortalityPregnancyNeurotoxinsTetanus ToxinTetanus Toxoidmaternal immunisationmaternal mortalitymaternal tetanusneonatal mortalityneonatal tetanusstudy protocol

Identifiers

PMID31167857
PMCPMC6561463
OpenAlexW2948560094

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.