Evidence map›Paper›PMID 31167809›Full record

ArticleJournal of lipid research2019

Novel CB1-ligands maintain homeostasis of the endocannabinoid system in ω3- and ω6-long-chain-PUFA deficiency.

Ina Hammels, Erika Binczek, Inga Schmidt-Soltau, Britta Jenke, Andreas Thomas, Matthias Vogel, Mario Thevis, Dilyana Filipova, Symeon Papadopoulos, Wilhelm Stoffel

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of lipid research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Ina HammelsCenter of Molecular Medicine (CMMC), Laboratory of Molecular Neurosciences, Institute of Biochemistry, University of Cologne, 50931 Cologne, Germany.
Erika BinczekCenter of Molecular Medicine (CMMC), Laboratory of Molecular Neurosciences, Institute of Biochemistry, University of Cologne, 50931 Cologne, Germany.
Inga Schmidt-SoltauCenter of Molecular Medicine (CMMC), Laboratory of Molecular Neurosciences, Institute of Biochemistry, University of Cologne, 50931 Cologne, Germany.
Britta JenkeCenter of Molecular Medicine (CMMC), Laboratory of Molecular Neurosciences, Institute of Biochemistry, University of Cologne, 50931 Cologne, Germany.
Andreas ThomasInstitute of Biochemistry Deutsche Sporthochschule (DSHS) Cologne, 50933 Cologne, Germany.
Matthias VogelInstitute of Biochemistry Deutsche Sporthochschule (DSHS) Cologne, 50933 Cologne, Germany.
Mario ThevisInstitute of Biochemistry Deutsche Sporthochschule (DSHS) Cologne, 50933 Cologne, Germany.
Dilyana FilipovaInstitute of Vegetative Physiology, Center of Physiology and Pathophysiology, University of Cologne, 50931 Cologne, Germany.
Symeon PapadopoulosInstitute of Vegetative Physiology, Center of Physiology and Pathophysiology, University of Cologne, 50931 Cologne, Germany.
Wilhelm StoffelCenter of Molecular Medicine (CMMC), Laboratory of Molecular Neurosciences, Institute of Biochemistry, University of Cologne, 50931 Cologne, Germany wilhelm.stoffel@uni-koeln.de.
University of Cologne · DEGerman Sport University Cologne · DECologne Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mammalian ω3- and ω6-PUFAs are synthesized from essential fatty acids (EFAs) or supplied by the diet. PUFAs are constitutive elements of membrane architecture and precursors of lipid signaling molecules. EFAs and long-chain (LC)-PUFAs are precursors in the synthesis of endocannabinoid ligands of G

Indexed as

AnimalsEndocannabinoidsFatty Acid DesaturasesFatty Acids, Omega-3Fatty Acids, Omega-6HEK293 CellsHumansMiceMice, KnockoutReceptor, Cannabinoid, CB1Receptor, Cannabinoid, CB2EndocannabinoidsFADS2 protein, mouseFatty Acid DesaturasesFatty Acids, Omega-3Fatty Acids, Omega-6Receptor, Cannabinoid, CB1Receptor, Cannabinoid, CB220:35,11,14-endocannabinoidsarachidonic acidcannabinoid receptor 1diet effectsendocannabinoid system-orexin-circuitryfatty acid desaturase 2-deficient mouse modellipid metabolismpolyunsaturated fatty acidsurrogate cannabinoid receptor 1 ligandsω3 fatty acids

Identifiers

PMID31167809
PMCPMC6672042
OpenAlexW2948914061

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.