ArticleThe Journal of biological chemistry2019
Molecular mechanism of
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Article in The Journal of biological chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
6.1field-weighted citation impact, top 3% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 65 citations in OpenAlex.
- Bacillus cereus PelAThe Journal of biological chemistry · 2026Article
- Synthesis and Immunological Evaluation of Pel-Derived Glycoconjugate Vaccine Candidates againstJACS Au · 2026Article
- Auto-aggregation inmBio · 2025Article
- Article
- Structural and functional analysis of Pseudomonas aeruginosa PelA provides insight into the modification of the Pel exopolysaccharide.The Journal of biological chemistry · 2025Article
- Structures of α-galactosaminidases from the CAZy GH114 family and homologs defining a new GH191 family of glycosidases.Acta crystallographica. Section D, Structural biology · 2025Article
- Recent developments inMicrobiology and molecular biology reviews : MMBR · 2025Review
- Characterization of theMicroorganisms · 2024Article
- CD56-mediated activation of human natural killer cells is triggered by Aspergillus fumigatus galactosaminogalactan.PLoS pathogens · 2024Article
- UnderstandingCell surface (Amsterdam, Netherlands) · 2023Review
- Pseudomonas aeruginosa biofilm exopolysaccharides: assembly, function, and degradation.FEMS microbiology reviews · 2023Review
- Strategy to combat biofilms: a focus on biofilm dispersal enzymes.NPJ biofilms and microbiomes · 2023Review
- Small Molecule Inhibition of an Exopolysaccharide Modification Enzyme is a Viable Strategy To Block Pseudomonas aeruginosa Pel Biofilm Formation.Microbiology spectrum · 2023Article
- How Three Self-Secreted Biofilm Exopolysaccharides ofInternational journal of molecular sciences · 2023Review
- Polysaccharides' Structures and Functions in Biofilm Architecture of Antimicrobial-Resistant (AMR) Pathogens.International journal of molecular sciences · 2023Review
- Glycoside hydrolase processing of the Pel polysaccharide alters biofilm biomechanics and Pseudomonas aeruginosa virulence.NPJ biofilms and microbiomes · 2023Article
- Identification of Compounds PreventingInternational journal of molecular sciences · 2023Article
- Filamentous fungal biofilms: Conserved and unique aspects of extracellular matrix composition, mechanisms of drug resistance and regulatory networks in Aspergillus fumigatus.NPJ biofilms and microbiomes · 2022Review
- Preclinical Evaluation of Recombinant Microbial Glycoside Hydrolases as Antibiofilm Agents in Acute Pulmonary Pseudomonas aeruginosa Infection.Antimicrobial agents and chemotherapy · 2022Article
- The Pel polysaccharide is predominantly composed of a dimeric repeat of α-1,4 linked galactosamine and N-acetylgalactosamine.Communications biology · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 5 institutions in 3 countries.
François Le MauffDepartment of Microbiology and Immunology, Faculty of Medicine, McGill University, Montreal, H3A 2B4 Quebec, Canada,; Infectious Disease and Immunity in Global Health, Research Institute of McGill University Health Center, Montreal, H4A 3J1 Quebec, Canada,; McGill Interdisciplinary Initiative in Infection and Immunity, Montreal, H3A 1Y2 Quebec, Canada.
Natalie C BamfordProgram in Molecular Medicine, The Hospital for Sick Children, Toronto, M5G 1X8 Ontario, Canada,; Department of Biochemistry, Faculty of Medicine, University of Toronto, Toronto, M5S 1A8 Ontario, Canada.
Noor AlnabelseyaProgram in Molecular Medicine, The Hospital for Sick Children, Toronto, M5G 1X8 Ontario, Canada,; Department of Biochemistry, Faculty of Medicine, University of Toronto, Toronto, M5S 1A8 Ontario, Canada.
Yongzhen ZhangLeiden Institute of Chemistry, Leiden University, 2300RA Leiden, The Netherlands, and.
Perrin BakerProgram in Molecular Medicine, The Hospital for Sick Children, Toronto, M5G 1X8 Ontario, Canada.
Howard RobinsonPhoton Science Division, Brookhaven National Laboratory, Upton, New York 11973-5000.
Jeroen D C CodéeLeiden Institute of Chemistry, Leiden University, 2300RA Leiden, The Netherlands, and.
P Lynne HowellProgram in Molecular Medicine, The Hospital for Sick Children, Toronto, M5G 1X8 Ontario, Canada,; Department of Biochemistry, Faculty of Medicine, University of Toronto, Toronto, M5S 1A8 Ontario, Canada,. Electronic address: howell@sickkids.ca.
Donald C SheppardDepartment of Microbiology and Immunology, Faculty of Medicine, McGill University, Montreal, H3A 2B4 Quebec, Canada,; Infectious Disease and Immunity in Global Health, Research Institute of McGill University Health Center, Montreal, H4A 3J1 Quebec, Canada,; McGill Interdisciplinary Initiative in Infection and Immunity, Montreal, H3A 1Y2 Quebec, Canada,. Electronic address: donald.sheppard@mcgill.ca.
University of Toronto · CALeiden University · NLMcGill University Health Centre · CABrookhaven National Laboratory · USHospital for Sick Children · CA
Funding
X-RAY STRUCTURE OF RIFM PROTEIN FROM THE BIOSYNTHESIS PATHWAY OF THE ANSAMYCIN AP41RR012408 · NCRR · BROOKHAVEN SCIENCE ASSOC-BROOKHAVEN LAB · PI ORVILLE, ALLEN M · 1998 to 2011
$32.2MCase Center for Synchrotron BiosciencesP30EB009998 · NIBIB · CASE WESTERN RESERVE UNIVERSITY · PI CHANCE, MARK R · 2009 to 2018
$8.4MMacromolecular Crystallography at the National Synchrotron Light SourceP41GM103473 · NIGMS · BROOKHAVEN SCIENCE ASSOC-BROOKHAVEN LAB · PI SWEET, ROBERT M · 2012 to 2013
$4.9MCIHR 123306CIHR 43998CIHR 81361CIHR FDN-154327CIHR FDN-159902NCRR NIH HHS P41 RR012408NIBIB NIH HHS P30 EB009998NIGMS NIH HHS P41 GM103473
Abstract
During infection, the fungal pathogen
Indexed as
Anti-Infective AgentsAspergillus fumigatusBiofilmsCatalytic DomainFungal ProteinsFungiGlycoside HydrolasesHydrolysisPolysaccharide-LyasesPolysaccharidesPseudomonas aeruginosaSpectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationSubstrate SpecificityVirulenceAnti-Infective AgentsFungal ProteinsgalactosaminogalactanGlycoside Hydrolasespectate lyasePolysaccharide-LyasesPolysaccharidesAspergillusbiofilmextracellular matrixgalactosaminogalactanglycoside hydrolaselung infectionprotein structuresubstrate specificityvirulence factor
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.