Evidence map›Paper›PMID 31167782›Full record

ArticleThe Journal of biological chemistry2019

GluN2A-NMDA receptor-mediated sustained Ca

Satya Narayan Deep, Sumonto Mitra, Sathyanarayanan Rajagopal, Surojit Paul, Ranjana Poddar

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Satya Narayan DeepDepartment of Neurology, University of New Mexico Health Sciences Center, Albuquerque, New Mexico 87131.
Sumonto MitraDepartment of Neurology, University of New Mexico Health Sciences Center, Albuquerque, New Mexico 87131.
Sathyanarayanan RajagopalDepartment of Neurology, University of New Mexico Health Sciences Center, Albuquerque, New Mexico 87131.
Surojit PaulDepartment of Neurology, University of New Mexico Health Sciences Center, Albuquerque, New Mexico 87131.
Ranjana PoddarDepartment of Neurology, University of New Mexico Health Sciences Center, Albuquerque, New Mexico 87131 rpoddar@salud.unm.edu.
University of New Mexico · US

Funding

Role of Brain Specific Tyrosne Phosphatase STEP in Neuroprotection and DeathR01NS059962 · NINDS · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI PAUL, SUROJIT · 2008 to 2023
$5.9M
Molecular basis of hyperhomocysteinemia induced brain injury in ischemic strokeR01NS083914 · NINDS · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI PODDAR, RANJANA · 2014 to 2025
$4.5M
NINDS NIH HHS R01 NS059962NINDS NIH HHS R01 NS083914
6 · The paper itself

Abstract

Homocysteine, a metabolite of the methionine cycle, is a known agonist of

Indexed as

AnimalsCalciumCell DeathEnzyme ActivationFemaleHomocysteineIon TransportMiceMice, KnockoutMitogen-Activated Protein KinasesNeuronsPhosphorylationPregnancyRatsRats, Sprague-DawleyReceptors, N-Methyl-D-AspartateCalciumHomocysteineMitogen-Activated Protein KinasesReceptors, N-Methyl-D-Aspartatecalciumcalcium homeostasisextracellular-signal-regulated kinase (ERK)GluN2A-NMDA receptor subunitglutamatehomocysteinehyperhomocysteinemiakinase signalingneurotoxicityN-methyl-D-aspartate receptor (NMDA receptor, NMDAR)

Identifiers

PMID31167782
PMCPMC6643025
OpenAlexW2948969934

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.