Evidence map›Paper›PMID 31167511›Full record

ArticleCancers2019

Human Colorectal Carcinoma Infiltrating B Lymphocytes Are Active Secretors of the Immunoglobulin Isotypes A, G, and M.

Christina Susanne Mullins, Michael Gock, Mathias Krohn, Michael Linnebacher

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Multimarker Assessment of B-Cell and Plasma Cell Subsets and Their Prognostic Role in the Colorectal Cancer Microenvironment.Clinical cancer research : an official journal of the American Association for Cancer Research · 2025
    Article
  2. Dysfunctional CD11cScience translational medicine · 2025
    Article
  3. Review
  4. Article
  5. Review
  6. The inflammatory pathogenesis of colorectal cancer.Nature reviews. Immunology · 2021
    Review
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Christina Susanne MullinsDepartment of General Surgery, Molecular Oncology and Immunotherapy, University Medicine Rostock, Schillingallee 69, 18057 Rostock, Germany. christina.mullins@med.uni-rostock.de.
Michael GockDepartment of General Surgery, University Medicine Rostock, Schillingallee 35, 18057 Rostock, Germany. michael.gock@med.uni-rostock.de.
Mathias KrohnDepartment of General Surgery, Molecular Oncology and Immunotherapy, University Medicine Rostock, Schillingallee 69, 18057 Rostock, Germany. mathias.krohn@med.uni-rostock.de.
Michael LinnebacherDepartment of General Surgery, Molecular Oncology and Immunotherapy, University Medicine Rostock, Schillingallee 69, 18057 Rostock, Germany. michael.linnebacher@med.uni-rostock.de.
University of Rostock · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite the importance of tumor infiltrating B cells (TiBc) in immunological circuits, their functional role is scarcely investigated. Here, we analyzed immunoglobulin (Ig) secretion of the subtypes IgA, IgG, and IgM of TiBc from freshly resected primary and secondary colorectal carcinomas (CRC) by FluoroSpot (

Indexed as

B cellscolorectal carcinomaFluoroSpottumor infiltrating lymphocytestumor microenvironment

Identifiers

PMID31167511
PMCPMC6627757
OpenAlexW2948834371

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.