Evidence map›Paper›PMID 31167464›Full record

ReviewViruses2019

Mast Cells and Natural Killer Cells-A Potentially Critical Interaction.

Liliana Portales-Cervantes, Bassel Dawod, Jean S Marshall

Open access · goldAbstract readReview
In one paragraph

Review in Viruses, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 29 citations in OpenAlex.

  1. Mast cell driven immunometabolism as a therapeutic entry point in ESCC.Frontiers in cell and developmental biology · 2026
    Review
  2. Review
  3. Innate Immune and Inflammatory Responses to Dengue Virus Infection.Current topics in microbiology and immunology · 2026
    Review
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  6. Observational
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  16. Mobilization and Activation of the Innate Immune Response to Dengue Virus.Frontiers in cellular and infection microbiology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Liliana Portales-CervantesDalhousie Human Immunology and Inflammation Group, Dalhousie University, Halifax, NS B3H 4R2, Canada. lportales@dal.ca.
Bassel DawodDepartment of Pathology, Dalhousie University, Halifax, NS B3H 4R2, Canada. dawod@dal.ca.
Jean S MarshallDalhousie Human Immunology and Inflammation Group, Dalhousie University, Halifax, NS B3H 4R2, Canada. jean.marshall@dal.ca.
Dalhousie University · CA

Funding

CIHR MOP93517
6 · The paper itself

Abstract

Natural killer (NK) cells play critical roles in host defense against infectious agents or neoplastic cells. NK cells provide a rapid innate immune response including the killing of target cells without the need for priming. However, activated NK cells can show improved effector functions. Mast cells are also critical for early host defense against a variety of pathogens and are predominately located at mucosal surfaces and close to blood vessels. Our group has recently shown that virus-infected mast cells selectively recruit NK cells and positively modulate their functions through mechanisms dependent on soluble mediators, such as interferons. Here, we review the possible consequences of this interaction in both host defense and pathologies involving NK cell and mast cell activation.

Indexed as

Immunity, InnateKiller Cells, NaturalMast CellsAnimalsAsthmaCytokinesHumansHypersensitivityInterferonsNeoplasmsOncolytic VirusesVirus DiseasesCytokinesInterferonscell recruitmentcellular activationCXCL8cytokinesinterferonsmast cellsNK cellsoncolytic virus

Identifiers

PMID31167464
PMCPMC6631774
OpenAlexW2948604111

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.