Evidence map›Paper›PMID 31167416›Full record

ArticleToxics2019

Levels of Cadmium in Human Mandibular Bone.

Andrew W Browar, Landon L Leavitt, Walter C Prozialeck, Joshua R Edwards

Open access · goldAbstract read
In one paragraph

Article in Toxics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Cadmium-Induced Proteinuria: Mechanistic Insights from Dose-Effect Analyses.International journal of molecular sciences · 2023
    Article
  5. Association amongInternational journal of environmental research and public health · 2022
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Andrew W BrowarCollege of Dental Medicine - Illinois, Midwestern University, 555 31st Street, Science Hall, Room 211-J, Downers Grove, IL 60515, USA. healthysmile@msn.com.ORCID 0000-0002-1615-0658
Landon L LeavittCollege of Dental Medicine - Illinois, Midwestern University, 555 31st Street, Science Hall, Room 211-J, Downers Grove, IL 60515, USA. lleavitt83@midwestern.edu.
Walter C ProzialeckDepartment of Pharmacology, College of Graduate Studies, Midwestern University, Downers Grove, IL 60515, USA. wprozi@midwestern.edu.
Joshua R EdwardsDepartment of Pharmacology, College of Graduate Studies, Midwestern University, Downers Grove, IL 60515, USA. jedwar@midwestern.edu.
Midwestern University · US

Funding

Midwestern University One Health Research Award
6 · The paper itself

Abstract

Cadmium (Cd) is an environmental toxicant that accumulates in bone and alters bone turnover and metabolism. Periodontal disease is characterized by tooth loss and tissue destruction, specifically, loss of supporting bone around the teeth. We have previously shown that Cd causes loss of dental alveolar (tooth supporting) bone in a rodent model of long-term Cd poisoning. The overall goal of this study was to determine the possible association between levels of Cd in alveolar bone and evidence of periodontal disease in human cadavers. The extent of Cd accumulation in human mandible samples was analyzed. Levels of Cd in mandibular alveolar bone were compared to those in basal bone as well as the renal cortex in samples obtained from the cadavers. Alveolar bone contained significantly higher levels of Cd when compared to basal bone (

Indexed as

bioaccumulationbody burdenbonecadmiumgender differencesmandibleOne Healthperiodontal disease

Identifiers

PMID31167416
PMCPMC6630888
OpenAlexW2948881806

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.