Evidence map›Paper›PMID 31167398›Full record

ArticlePharmaceuticals (Basel, Switzerland)2019

Voltammetric Evaluation of Diclofenac Tablets Samples through Carbon Black-Based Electrodes.

Carlos Eduardo Peixoto da Cunha, Edson Silvio Batista Rodrigues, Morgana Fernandes Alecrim, Douglas Vieira Thomaz, Isaac Yves Lopes Macêdo, Luane Ferreira Garcia, Jerônimo Raimundo de Oliveira Neto, Emily Kussmaul Gonçalves Moreno, Nara Ballaminut, Eric de Souza Gil

Abstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Carlos Eduardo Peixoto da CunhaFaculdade de Farmácia, Universidade Federal de Goiás, Goiânia, GO 74690-970, Brazil. cedcunhap35@hotmail.com.
Edson Silvio Batista RodriguesFaculdade de Farmácia, Universidade Federal de Goiás, Goiânia, GO 74690-970, Brazil. edson.silvio.b@gmail.com.
Morgana Fernandes AlecrimFaculdade de Farmácia, Universidade Federal de Goiás, Goiânia, GO 74690-970, Brazil. morgana.alecrim@hotmail.com.
Douglas Vieira ThomazFaculdade de Farmácia, Universidade Federal de Goiás, Goiânia, GO 74690-970, Brazil. douglasvthomaz@gmail.com.ORCID 0000-0003-0000-3466
Isaac Yves Lopes MacêdoFaculdade de Farmácia, Universidade Federal de Goiás, Goiânia, GO 74690-970, Brazil. isaacyvesl@gmail.com.
Luane Ferreira GarciaFaculdade de Farmácia, Universidade Federal de Goiás, Goiânia, GO 74690-970, Brazil. luane.fg@hotmail.com.
Jerônimo Raimundo de Oliveira NetoFaculdade de Farmácia, Universidade Federal de Goiás, Goiânia, GO 74690-970, Brazil. jeronimoneto8@gmail.com.
Emily Kussmaul Gonçalves MorenoFaculdade de Farmácia, Universidade Federal de Goiás, Goiânia, GO 74690-970, Brazil. milykussmaul@gmail.com.
Nara BallaminutFaculdade de Farmácia, Universidade Federal de Goiás, Goiânia, GO 74690-970, Brazil. naraballaminut@gmail.com.
Eric de Souza GilFaculdade de Farmácia, Universidade Federal de Goiás, Goiânia, GO 74690-970, Brazil. ericsgil@gmail.com.ORCID 0000-0001-9161-0127

Funding

CNPq 409287/2018-0Fapeg and Capes scolarships
6 · The paper itself

Abstract

Diclofenac (DIC) is a non-steroidal anti-inflammatory drug of wide use around the world. Electroanalytical methods display a high analytical potential for application in pharmaceutical samples but the drawbacks concerning electrode fouling and reproducibility are of major concern. Henceforth, the aim of this work was to propose the use of alternative low-cost carbon black (CB) and ionic liquid (IL) matrix to modify the surface of pencil graphite electrodes (PGE) in order to quantify DIC in raw materials, intermediates, and final products, as well as in stability assays of tablets. The proposed method using CB+IL/PGE displayed good recovery (99.4%) as well as limits of detection (LOD) of 0.08 µmol L-1 and limits of quantification (LOQ) of 0.28 µmol L

Indexed as

anti-inflammatory drugspencil graphite electrodespharmaceutical electroanalysisstability assays

Identifiers

PMID31167398
PMCPMC6630689

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.