Evidence map›Paper›PMID 31167180›Full record

ArticleAmerican journal of nephrology2019

Albuminuria Testing by Race and Ethnicity among Patients with Hypertension with and without Diabetes.

Joi Lee, Chi Chu, David Guzman, Valy Fontil, Alexandra Velasquez, Neil R Powe, Delphine S Tuot

Open access · bronzeAbstract read
In one paragraph

Article in American journal of nephrology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 2 pooled it
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  8. Factors Associated With Non-vaccination for Influenza Among Patients With CKD: Findings From the Chronic Renal Insufficiency Cohort (CRIC) Study.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2024
    Observational
  9. Epidemiology of Diabetic Kidney Disease among US Veterans.Diabetes, metabolic syndrome and obesity : targets and therapy · 2024
    Article
  10. Article
  11. Fulfillment and Validity of the Kidney Health Evaluation Measure for People with Diabetes.Mayo Clinic proceedings. Innovations, quality & outcomes · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Joi LeeUCSF, Division of Nephrology at Zuckerberg San Francisco General Hospital, San Francisco, California, USA.
Chi ChuUCSF, Division of Nephrology at Zuckerberg San Francisco General Hospital, San Francisco, California, USA.
David GuzmanUCSF Division of General Internal Medicine at Zuckerberg San Francisco General Hospital, San Francisco, California, USA.
Valy FontilUCSF Division of General Internal Medicine at Zuckerberg San Francisco General Hospital, San Francisco, California, USA.
Alexandra VelasquezUCSF, Division of Nephrology at Zuckerberg San Francisco General Hospital, San Francisco, California, USA.
Neil R PoweUCSF Division of General Internal Medicine at Zuckerberg San Francisco General Hospital, San Francisco, California, USA.
Delphine S TuotUCSF, Division of Nephrology at Zuckerberg San Francisco General Hospital, San Francisco, California, USA, delphine.tuot@ucsf.edu.
San Francisco General Hospital · US

Funding

Academic Training Program in NephrologyT32DK007219 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HSU, CHI-YUAN · 1986 to 2022
$7.3M
SF BUILD: Enabling Students to Represent in ScienceTL4GM118986 · NIGMS · SAN FRANCISCO STATE UNIVERSITY · PI MARQUEZ-MAGANA, LETICIA MARIA, MORRIS, MEGHAN D · 2015 to 2022
$5.4M
Kidney Awareness Registry and Education-2R01DK104130 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI TUOT, DELPHINE · 2015 to 2019
$2.8M
Bring it Down San Francisco: Harnessing cloud-based technology to improve hypertension management in a low-income underserved populationK23HL136899 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FONTIL, VALY · 2018 to 2022
$887k
NHLBI NIH HHS K23 HL136899NIDDK NIH HHS R01 DK104130NIDDK NIH HHS T32 DK007219NIGMS NIH HHS TL4 GM118986
6 · The paper itself

Abstract

backgroundDetection of chronic kidney disease (CKD) with urine albumin-to-creatinine ratio (UACR) among patients with hypertension (HTN) provides an opportunity for early treatment, potentially mitigating risk of CKD progression and cardiovascular complications. Differences in UACR testing patterns among racial/ethnic populations at risk for CKD could contribute to known disparities in CKD complications.

methodsWe examined the prevalence of UACR testing among low-income adult primary care patients with HTN, defined by a new administrative code for HTN or 2 clinic blood pressures >140/90 mm Hg between January 1, 2014, and January 1, 2017, in one public health-care delivery system with a high prevalence of end-stage kidney disease among race/ethnic minorities. Logistic regression was used to identify odds of UACR testing within 1 year of a HTN diagnosis, overall, and by racial/ethnic subgroup, adjusted for demographic factors, estimated glomerular filtration rate, and HTN severity. Models were also stratified by diabetes status.

resultsThe cohort (n = 16,414) was racially/ethnically diverse (16% White, 21% Black, 34% Asian, 19% Hispanic, and 10% other) and 51% female. Only 35% of patients had UACR testing within 1 year of a HTN diagnosis. Among individuals without diabetes, odds of UACR testing were higher among Asians, Blacks, and Other subgroups compared to Whites (adjusted OR [aOR] 1.19; 95% CI 1.00-1.42 for Blacks; aOR 1.33; 1.13-1.56 for Asians; aOR 1.30; 1.04-1.60 for Other) but were not significantly different between Hispanics and Whites (aOR 1.17; 0.97-1.39). Among individuals with diabetes, only Asians had higher odds of UACR testing compared to Whites (aOR 1.35; 1.12-1.63).

conclusionsPrevalence of UACR testing among low-income patients with HTN is low in one public health-care delivery system, with higher odds of UACR testing among racial/ethnic minority subgroups compared to Whites without diabetes and similar odds among those with diabetes. If generalizable, less albuminuria testing may not explain higher prevalence of kidney failure in racial/ethnic minorities.

Indexed as

AdolescentAdultAgedAged, 80 and overAlbuminuriaAsian PeopleBlack or African AmericanCreatineCross-Sectional StudiesDiabetic NephropathiesFemaleGlomerular Filtration RateHealthcare DisparitiesHealth Status DisparitiesHispanic or LatinoHumansCreatineSerum Albumin, HumanAlbuminuria testingChronic kidney diseaseChronic kidney disease disparitiesDiabetesHypertensionRacial disparitiesSafety-net clinicVulnerable populations

Identifiers

PMID31167180
PMCPMC6620121
OpenAlexW2958221964

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.