Evidence map›Paper›PMID 31167123›Full record

ArticleStructure (London, England : 1993)2019

A Viral Protein Mimics Histone to Hijack Host MORC3.

Liang Zhu, Jun Qin

Open access · bronzeAbstract readComment
PubMed Publisher
In one paragraph

Article in Structure (London, England : 1993), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Vital for Viruses: Intrinsically Disordered Proteins.Journal of molecular biology · 2023
    Review
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Liang ZhuDepartment of Cardiovascular & Metabolic Sciences, Lerner Research Institute, Cleveland Clinic, 9500 Euclid Ave., Cleveland, OH 44195, USA.
Jun QinDepartment of Cardiovascular & Metabolic Sciences, Lerner Research Institute, Cleveland Clinic, 9500 Euclid Ave., Cleveland, OH 44195, USA. Electronic address: qinj@ccf.org.
Cleveland Clinic Lerner College of Medicine · US

Funding

Structure Basis for Talin-mediated Integrin ActivationP01HL073311 · NHLBI · CLEVELAND CLINIC LERNER COM-CWRU · PI BYZOVA, TATIANA V · 2004 to 2019
$27.4M
NMR Structural Elucidation of Integrin ActivationR01GM062823 · NIGMS · CLEVELAND CLINIC LERNER COM-CWRU · PI QIN, JUN · 2002 to 2018
$5.1M
NHLBI NIH HHS P01 HL073311NIGMS NIH HHS R01 GM062823
6 · The paper itself

Abstract

Microrchidia 3 (MORC3) is an ATPase and a regulator of influenza A virus (IAVs). In this issue of Structure, Zhang et al. (2019b) solved the crystal structure of human MORC3 in complex with the IAV protein NS1, providing a mechanism for targeting MORC3 by IAVs to regulate viral infection.

Indexed as

Influenza A virusInfluenza, HumanAdenosine TriphosphatasesDNA-Binding ProteinsHistonesHumansViral ProteinsAdenosine TriphosphatasesDNA-Binding ProteinsHistonesMORC3 protein, humanViral Proteins

Identifiers

PMID31167123
OpenAlexW2948952965

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.