Evidence map›Paper›PMID 31166845›Full record

ArticleMolecular biology of the cell2019

Rho-dependent control of the Citron kinase, Sticky, drives midbody ring maturation.

Nour El-Amine, Sabrya C Carim, Denise Wernike, Gilles R X Hickson

Open access · greenAbstract read
In one paragraph

Article in Molecular biology of the cell, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Nour El-AmineCentre de Cancérologie Charles Bruneau, Centre Hospitalier Universitaire Sainte-Justine Centre de Recherche, Montréal, QC H3T 1C5, Canada.
Sabrya C CarimCentre de Cancérologie Charles Bruneau, Centre Hospitalier Universitaire Sainte-Justine Centre de Recherche, Montréal, QC H3T 1C5, Canada.
Denise WernikeCentre de Cancérologie Charles Bruneau, Centre Hospitalier Universitaire Sainte-Justine Centre de Recherche, Montréal, QC H3T 1C5, Canada.
Gilles R X HicksonCentre de Cancérologie Charles Bruneau, Centre Hospitalier Universitaire Sainte-Justine Centre de Recherche, Montréal, QC H3T 1C5, Canada.
Centre Hospitalier Universitaire Sainte-Justine · CA

Funding

CIHR MOP-97788
6 · The paper itself

Abstract

Rho-dependent proteins control assembly of the cytokinetic contractile ring, yet it remains unclear how those proteins guide ring closure and how they promote subsequent formation of a stable midbody ring. Citron kinase is one important component required for midbody ring formation but its mechanisms of action and relationship with Rho are controversial. Here, we conduct a structure-function analysis of the

Indexed as

ActomyosinAnimalsCell LineContractile ProteinsCytokinesisDrosophila melanogasterDrosophila ProteinsGuanine Nucleotide Exchange FactorsIntracellular Signaling Peptides and ProteinsProtein Serine-Threonine KinasesRho FactorRNA InterferenceStructure-Activity RelationshipActomyosinanillincitron-kinaseContractile ProteinsDrosophila ProteinsGuanine Nucleotide Exchange FactorsIntracellular Signaling Peptides and ProteinsPbl protein, DrosophilaProtein Serine-Threonine KinasesRho Factor

Identifiers

PMID31166845
PMCPMC6743463
OpenAlexW2951705370

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.