Evidence map›Paper›PMID 31166819›Full record

ReviewJournal of neurophysiology2019

Age-related changes in leg proprioception: implications for postural control.

Mélanie Henry, Stéphane Baudry

3 registry-linked trialsOpen access · bronzeAbstract readReview
In one paragraph

Review in Journal of neurophysiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 150 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
150citing papers in PubMed, 3 pooled it
45.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05544630 unknown statusnot on this mapstarted 2022, after this paper: background citation

Effect of Aging on Postural Stability

TypeobservationalSponsorSohag UniversityRan2022 to 2023Enrolled30ConditionsEffect of Aging on Postural StabilityArmscomputerized dynamic posturography (sensory orgnization test)
NCT07150364 narecruitingnot on this mapstarted 2024, after this paper: background citation

Comparison of Square Stepping Exercise and Wobble Board Exercise on Cognition, Balance and Fall Risk in Elderly Population

TypeinterventionalSponsorRiphah International UniversityRan2024 to 2026Enrolled38ConditionsElderly PopulationArmsSquare Stepping Exercise, Wobble Board Exercise
NCT07309068 nacompletednot on this mapstarted 2025, after this paper: background citation

Acute Effects of Blood Flow Restriction Training on Balance and Proprioception: A Randomized Controlled Blinded StudyAcute BFR Training Effects on Balance and Proprioception

TypeinterventionalSponsorBiruni UniversityRan2025 to 2026Enrolled74ConditionsBlood Flow RestrictionArmsBFR, sham BFR, Proprioceptive Exercise Training
3 · Its place in the literature

Who cites it

150 citing papers in PubMed, 3 syntheses or guidelines pooled it, 287 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
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  7. Low-Intensity Blood Flow-Restricted Multi-Joint Exercise Improves Muscle Function in Patients With Patellofemoral Pain Syndrome: A Randomized Trial.Medical science monitor : international medical journal of experimental and clinical research · 2026
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  12. Review
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  16. Postural sway changes and quality of life measures in older women with chronic low back pain.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  17. Review
  18. Walking as a Window to the Brain: Redefining Gait in Neurology.Medical sciences (Basel, Switzerland) · 2026
    Review
  19. Article
  20. Article

90 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Mélanie HenryLaboratory of Applied Biology and Research Unit in Applied Neurophysiology, ULB Neuroscience Institute, Université libre de Bruxelles, Brussels, Belgium.
Stéphane BaudryLaboratory of Applied Biology and Research Unit in Applied Neurophysiology, ULB Neuroscience Institute, Université libre de Bruxelles, Brussels, Belgium.
Université Libre de Bruxelles · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In addition to being a prerequisite for many activities of daily living, the ability to maintain steady upright standing is a relevant model to study sensorimotor integrative function. Upright standing requires managing multimodal sensory inputs to produce finely tuned motor output that can be adjusted to accommodate changes in standing conditions and environment. The sensory information used for postural control mainly arises from the vestibular system of the inner ear, vision, and proprioception. Proprioception (sense of body position and movement) encompasses signals from mechanoreceptors (proprioceptors) located in muscles, tendons, and joint capsules. There is general agreement that proprioception signals from leg muscles provide the primary source of information for postural control. This is because of their exquisite sensitivity to detect body sway during unperturbed upright standing that mainly results from variations in leg muscle length induced by rotations around the ankle joint. However, aging is associated with alterations of muscle spindles and their neural pathways, which induce a decrease in the sensitivity, acuity, and integration of the proprioceptive signal. These alterations promote changes in postural control that reduce its efficiency and thereby may have deleterious consequences for the functional independence of an individual. This narrative review provides an overview of how aging alters the proprioceptive signal from the legs and presents compelling evidence that these changes modify the neural control of upright standing.

Indexed as

Standing PositionAgingHumansLegMuscle SpindlesPostural BalanceProprioceptionbalanceIa afferentsmuscle spindlesproprioceptionupright standing

Identifiers

PMID31166819
PMCPMC6734411
OpenAlexW2948599889

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.