ReviewJournal of biomechanical engineering2019
Deciphering the "Art" in Modeling and Simulation of the Knee Joint: Overall Strategy.
Review in Journal of biomechanical engineering, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed.
- Rapid personalized computational modeling of the wrist.Medical engineering & physics · 2026Article
- Artificial Intelligence Models for Classifying Wrist Ligament Injuries Using Synthetically-Generated Joint Proximity Maps from Finite Element Models.bioRxiv : the preprint server for biology · 2026Article
- Deciphering the "Art" in Modeling and Simulation of the Knee Joint: Model Benchmarking.Journal of biomechanical engineering · 2026Article
- Evidence-informed methodological approaches for coupled neuromusculoskeletal-finite element analysis workflows in orthopaedic biomechanics.Frontiers in bioengineering and biotechnology · 2026Article
- Cartilage mechanical responses during gait as in silico biomarkers for medial knee OA progression.Scientific reports · 2025Article
- Efficient development of subject-specific finite element knee models: Automated identification of soft-tissue attachments.Journal of biomechanics · 2025Article
- Validating subject-specific knee models fromFrontiers in bioengineering and biotechnology · 2025Article
- Impact of knee geometry on joint contact mechanics after meniscectomy.Scientific reports · 2024Article
- Recent developments in computational modelling of the knee.Osteoarthritis imaging · 2024Article
- Automated 2D and 3D finite element overclosure adjustment and mesh morphing using generalized regression neural networks.Medical engineering & physics · 2024Article
- Integration of Swin UNETR and statistical shape modeling for a semi-automated segmentation of the knee and biomechanical modeling of articular cartilage.Scientific reports · 2024Article
- Reproducibility in modeling and simulation of the knee: Academic, industry, and regulatory perspectives.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2023Review
- Deciphering the "Art" in Modeling and Simulation of the Knee Joint: Assessing Model Calibration Workflows and Outcomes.Journal of biomechanical engineering · 2023Article
- Validation and evaluation of subject-specific finite element models of the pediatric knee.Scientific reports · 2023Article
- Towards a Transferable Modeling Method of the Knee to Distinguish Between Future Healthy Joints from Osteoarthritic Joints: Data from the Osteoarthritis Initiative.Annals of biomedical engineering · 2023Article
- Assessment of reporting practices and reproducibility potential of a cohort of published studies in computational knee biomechanics.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2023Article
- Signatures of disease progression in knee osteoarthritis: insights from an integrated multi-scale modeling approach, a proof of concept.Frontiers in bioengineering and biotechnology · 2023Article
- A Parameter Sensitivity Analysis on Multiple Finite Element Knee Joint Models.Frontiers in bioengineering and biotechnology · 2022Article
- Apparatus for In Vivo Knee Laxity Assessment Using High-Speed Stereo Radiography.Journal of medical devices · 2021Article
- A Method to Compare Heterogeneous Types of Bone and Cartilage Meshes.Journal of biomechanical engineering · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
Recent explorations of knee biomechanics have benefited from computational modeling, specifically leveraging advancements in finite element analysis and rigid body dynamics of joint and tissue mechanics. A large number of models have emerged with different levels of fidelity in anatomical and mechanical representation. Adapted modeling and simulation processes vary widely, based on justifiable choices in relation to anticipated use of the model. However, there are situations where modelers' decisions seem to be subjective, arbitrary, and difficult to rationalize. Regardless of the basis, these decisions form the "art" of modeling, which impact the conclusions of simulation-based studies on knee function. These decisions may also hinder the reproducibility of models and simulations, impeding their broader use in areas such as clinical decision making and personalized medicine. This document summarizes an ongoing project that aims to capture the modeling and simulation workflow in its entirety-operation procedures, deviations, models, by-products of modeling, simulation results, and comparative evaluations of case studies and applications. The ultimate goal of the project is to delineate the art of a cohort of knee modeling teams through a publicly accessible, transparent approach and begin to unravel the complex array of factors that may lead to a lack of reproducibility. This manuscript outlines our approach along with progress made so far. Potential implications on reproducibility, on science, engineering, and training of modeling and simulation, on modeling standards, and on regulatory affairs are also noted.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.