Evidence map›Paper›PMID 31166406›Full record

ArticleAnais brasileiros de dermatologia2019

Consensus on the therapeutic management of atopic dermatitis - Brazilian Society of Dermatology.

Valeria Aoki, Daniel Lorenzini, Raquel Leão Orfali, Mariana Colombini Zaniboni, Zilda Najjar Prado de Oliveira, Maria Cecília Rivitti-Machado, Roberto Takaoka, Magda Blessmann Weber, Tania Cestari, Bernardo Gontijo and 8 more

2 registry-linked trialsOpen access · goldAbstract readConsensus Statement
In one paragraph

Article in Anais brasileiros de dermatologia, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04950374 nawithdrawnnot on this mapstarted 2021, after this paper: background citation

Single Center, Open-label, Non-randomized Clinical Trial to Evaluate the Safety and Efficacy of a Moisturizer Body Lotion and the Safety and Perceived Efficacy of a Lip Moisturizer in Adults With Atopic Dermatitis Presenting Dermatological Lesion.

TypeinterventionalSponsorJohnson & Johnson Consumer Inc. (J&JCI)Ran2021 to 2021Enrolled0ConditionsAtopic DermatitisArmsMoisturizer Body Lotion, Lip Moisturizer
NCT05062213 nacompletednot on this mapstarted 2021, after this paper: background citation

Single Center, Open-label, Non-randomized Clinical Trial to Evaluate the Safety and Efficacy of a Moisturizer Body Lotion During and After 21 ± 2 Days of Use in Adults With Atopic Dermatitis.

TypeinterventionalSponsorJohnson & Johnson Consumer Inc. (J&JCI)Ran2021 to 2022Enrolled34ConditionsAtopic DermatitisArmsMoisturizer Body Lotion
3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. International consensus on methotrexate dosing for patients with atopic dermatitis: An eDelphi study.Journal of the European Academy of Dermatology and Venereology : JEADV · 2025
    Article
  6. Review
  7. Review
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Mesenchymal Stem Cells and Atopic Dermatitis: A Review.Frontiers in cell and developmental biology · 2020
    Review
  14. Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 11 institutions in 1 country.

Valeria AokiDepartment of Dermatology, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil.
Daniel LorenziniDermatology Service, Irmandade Santa Casa de Misericórdia de Porto Alegre, Porto Alegre, RS, Brazil.
Raquel Leão OrfaliDepartment of Dermatology, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil.
Mariana Colombini ZaniboniDepartment of Dermatology, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil.
Zilda Najjar Prado de OliveiraDepartment of Dermatology, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil.
Maria Cecília Rivitti-MachadoDepartment of Dermatology, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil.
Roberto TakaokaDepartment of Dermatology, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil.
Magda Blessmann WeberDermatology Service, Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, RS, Brazil.
Tania CestariDermatology Service, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.
Bernardo GontijoDermatology Service, Hospital das Clínicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.
Andrea Machado Coelho RamosDermatology Service, Hospital das Clínicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.
Claudia Marcia de Resende SilvaDermatology Service, Hospital das Clínicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.
Silmara da Costa Pereira CestariMedical Dermatology Residency Program, Instituto de Ensino e Pesquisa, Hospital Sírio-Libanês, São Paulo, SP, Brazil.
Silvia Souto-MayorClinic of Dermatology, Department of Medicine, Faculdade de Medicina da Santa Casa de São Paulo, São Paulo, SP, Brazil.
Francisca Regina CarneiroDermatology Service, Universidade do Estado do Pará, Belém, PA, Brazil.
Ana Maria Mosca de CerqueiraDermatology Service, Hospital Municipal Jesus, Rio de Janeiro, RJ, Brazil.
Cristina LaczynskiDermatology Outpatient Clinic, Faculdade de Medicina do ABC, Santo André, SP, Brazil.
Mario Cezar PiresDermatology Service, Hospital do Servidor Público Estadual, São Paulo, SP, Brazil.
Universidade de São Paulo · BRUniversidade Federal de Minas Gerais · BRFaculdade de Ciências Médicas da Santa Casa de São Paulo · BRFaculdade de Medicina do ABC · BRHospital do Servidor Público Estadual · BRHospital Geral de Bonsucesso · BRHospital Sírio-Libanês · BRIrmandade da Santa Casa de Misericórdia de São Paulo · BRUniversidade do Estado do Pará · BRUniversidade Federal de Ciências da Saúde de Porto Alegre · BRUniversidade Federal do Rio Grande do Sul · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAtopic dermatitis is a highly prevalent inflammatory and pruritic dermatosis with a multifactorial etiology, which includes skin barrier defects, immune dysfunction, and microbiome alterations. Atopic dermatitis is mediated by genetic, environmental, and psychological factors and requires therapeutic management that covers all the aspects of its complex pathogenesis.

objectivesThe aim of this article is to present the experience, opinions, and recommendations of Brazilian dermatology experts regarding the therapeutic management of atopic dermatitis.

methodsEighteen experts from 10 university hospitals with experience in atopic dermatitis were appointed by the Brazilian Society of Dermatology to organize a consensus on the therapeutic management of atopic dermatitis. The 18 experts answered an online questionnaire with 14 questions related to the treatment of atopic dermatitis. Afterwards, they analyzed the recent international guidelines on atopic dermatitis of the American Academy of Dermatology, published in 2014, and of the European Academy of Dermatology and Venereology, published in 2018. Consensus was defined as approval by at least 70% of the panel. RESULTS/

conclusionThe experts stated that the therapeutic management of atopic dermatitis is based on skin hydration, topical anti-inflammatory agents, avoidance of triggering factors, and educational programs. Systemic therapy, based on immunosuppressive agents, is only indicated for severe refractory disease and after failure of topical therapy. Early detection and treatment of secondary bacterial and viral infections is mandatory, and hospitalization may be needed to control atopic dermatitis flares. Novel target-oriented drugs such as immunobiologicals are invaluable therapeutic agents for atopic dermatitis.

Indexed as

Administration, TopicalAdrenal Cortex HormonesAnti-Infective AgentsAnti-Inflammatory AgentsBrazilCalcineurin InhibitorsDermatitis, AtopicDermatologyHumansSeverity of Illness IndexSocieties, MedicalUltraviolet TherapyAdrenal Cortex HormonesAnti-Infective AgentsAnti-Inflammatory AgentsCalcineurin Inhibitors

Identifiers

PMID31166406
PMCPMC6544038
OpenAlexW2947544047

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.