Evidence map›Paper›PMID 31165925›Full record

ReviewJournal of neurology2019

Endolymphatic hydrops and ionic transporters: genetic and biohumoral aspects.

Roberto Teggi, Simona Delli Carpini, Laura Zagato

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of neurology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 22 citations in OpenAlex.

  1. Genetic contributions to familial Ménière's disease: a systematic review.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Sensational site: the sodium pump ouabain-binding site and its ligands.American journal of physiology. Cell physiology · 2024
    Review
  6. Article
  7. Frontiers in neurology · 2023
    Article
  8. Article
  9. AFrontiers in cell and developmental biology · 2022
    Article
  10. Article
  11. Article
  12. Article
  13. Evaluation of a large cohort of adult patients with Ménière's disease: bedside and clinical history.Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2020
    Article
  14. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Roberto TeggiDepartment of Otolaryngology, IRCCS San Raffaele Scientific Institute, San Raffaele Hospital, via Olgettina 60, 20132, Milan, Italy. teggi.roberto@hsr.it.ORCID http://orcid.org/0000-0003-2948-4638
Simona Delli CarpiniGenomics of Renal Diseases and Hypertension Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Laura ZagatoGenomics of Renal Diseases and Hypertension Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Vita-Salute San Raffaele University · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ménière's disease (MD) is an inner ear disorder, characterized by a burden of symptoms, probably arising from the interplay of genetic and environmental factors. In this brief review, we consider the role of ion channels and transporters in the pathophysiology of MD, focusing on genetic and biohumoral aspects. Pathophysiological mechanisms related to altered concentrations of ions in the endolymph include altered osmotic pressure leading to hydrops and/or immunomodulatory effects of K

Indexed as

Aquaporin 2EndolymphEndolymphatic HydropsHumansIon ChannelsIon TransportMeniere DiseaseSodium-Calcium ExchangerAQP2 protein, humanAquaporin 2Ion ChannelsSodium-Calcium Exchangersodium-calcium exchanger 1AquaporinsEndogenous OuabainHydropsIonic exchangersMénière’s disease

Identifiers

PMID31165925
OpenAlexW2948201402

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.