Evidence map›Paper›PMID 31165910›Full record

ArticleEuropean biophysics journal : EBJ2019

Solution structure and backbone dynamics for S1 domain of ribosomal protein S1 from Mycobacterium tuberculosis.

Biling Huang, Shihui Fan, Yan Liu, Yufen Zhao, Donghai Lin, Xinli Liao

Abstract read
PubMed Publisher
In one paragraph

Article in European biophysics journal : EBJ, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Biling HuangDepartment of Chemical Biology, College of Chemistry and Chemical Engineering, Xiamen University, No. 422, Siming South Road, Xiamen, 361005, Fujian, People's Republic of China.ORCID http://orcid.org/0000-0002-1060-8787
Shihui FanDepartment of Chemical Biology, College of Chemistry and Chemical Engineering, Xiamen University, No. 422, Siming South Road, Xiamen, 361005, Fujian, People's Republic of China.
Yan LiuDepartment of Chemical Biology, College of Chemistry and Chemical Engineering, Xiamen University, No. 422, Siming South Road, Xiamen, 361005, Fujian, People's Republic of China.
Yufen ZhaoDepartment of Chemical Biology, College of Chemistry and Chemical Engineering, Xiamen University, No. 422, Siming South Road, Xiamen, 361005, Fujian, People's Republic of China. yfzhao@xmu.edu.cn.
Donghai LinDepartment of Chemical Biology, College of Chemistry and Chemical Engineering, Xiamen University, No. 422, Siming South Road, Xiamen, 361005, Fujian, People's Republic of China. dhlin@xmu.edu.cn.
Xinli LiaoDepartment of Chemical Biology, College of Chemistry and Chemical Engineering, Xiamen University, No. 422, Siming South Road, Xiamen, 361005, Fujian, People's Republic of China. xlliao@xmu.edu.cn.
Xiamen University · CNNingbo University · CN

Funding

National Key Research and Development Program of China 2016YFA0500600National Natural Science Foundation of China No. 21778042National Natural Science Foundation of China No. 31270777National Natural Science Foundation of China No. 41876072National Natural Science Foundation of China No. 91856126
6 · The paper itself

Abstract

The pro-drug pyrazinamide is hydrolyzed to pyrazinoic acid (POA) in its use for the treatment of tuberculosis. As a molecule with bactericidal activity, POA binds to the C-terminal S1 domain of ribosomal protein S1 from Mycobacterium tuberculosis (MtRpsA

Indexed as

Mycobacterium tuberculosisBacterial ProteinsBinding SitesLigandsModels, MolecularProtein DomainsRibosomal ProteinsSolutionsThermodynamicsBacterial ProteinsLigandsRibosomal Proteinsribosomal protein S1SolutionsBackbone dynamicsMtRpsA(369–481)MtRpsACTD_S1(280–368)NMRPyrazinoic acidSolution structureTrans-translation

Identifiers

PMID31165910
OpenAlexW2948101692

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.