Evidence map›Paper›PMID 31165736›Full record

ArticleCell death & disease2019

Fibrotic liver microenvironment promotes Dll4 and SDF-1-dependent T-cell lineage development.

Zheng Gong, Bingxue Shang, Yunpeng Chu, Xiaodong Chen, Qing Li, Keli Liu, Yongjing Chen, Yin Huang, Yanyan Han, Qianwen Shang and 11 more

Open access · goldAbstract read
In one paragraph

Article in Cell death & disease, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 95% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 5 institutions in 1 country.

Zheng GongThe First Affiliated Hospital of Soochow University, Institutes for Translational Medicine, State Key Laboratory of Radiation Medicine and Protection, Key Laboratory of Stem Cells and Medical Biomaterials of Jiangsu Province, Soochow University Medical College, Suzhou, China.
Bingxue ShangThe First Affiliated Hospital of Soochow University, Institutes for Translational Medicine, State Key Laboratory of Radiation Medicine and Protection, Key Laboratory of Stem Cells and Medical Biomaterials of Jiangsu Province, Soochow University Medical College, Suzhou, China.
Yunpeng ChuThe First Affiliated Hospital of Soochow University, Institutes for Translational Medicine, State Key Laboratory of Radiation Medicine and Protection, Key Laboratory of Stem Cells and Medical Biomaterials of Jiangsu Province, Soochow University Medical College, Suzhou, China.
Xiaodong ChenKey Laboratory of Tissue Microenvironment and Tumor, Institute of Health Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China.
Qing LiKey Laboratory of Tissue Microenvironment and Tumor, Institute of Health Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China.
Keli LiuKey Laboratory of Tissue Microenvironment and Tumor, Institute of Health Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China.
Yongjing ChenThe First Affiliated Hospital of Soochow University, Institutes for Translational Medicine, State Key Laboratory of Radiation Medicine and Protection, Key Laboratory of Stem Cells and Medical Biomaterials of Jiangsu Province, Soochow University Medical College, Suzhou, China.
Yin HuangKey Laboratory of Tissue Microenvironment and Tumor, Institute of Health Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China.ORCID http://orcid.org/0000-0001-5602-9871
Yanyan HanKey Laboratory of Tissue Microenvironment and Tumor, Institute of Health Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China.
Qianwen ShangThe First Affiliated Hospital of Soochow University, Institutes for Translational Medicine, State Key Laboratory of Radiation Medicine and Protection, Key Laboratory of Stem Cells and Medical Biomaterials of Jiangsu Province, Soochow University Medical College, Suzhou, China.
Zhiyuan ZhengThe First Affiliated Hospital of Soochow University, Institutes for Translational Medicine, State Key Laboratory of Radiation Medicine and Protection, Key Laboratory of Stem Cells and Medical Biomaterials of Jiangsu Province, Soochow University Medical College, Suzhou, China.
Lin SongThe First Affiliated Hospital of Soochow University, Institutes for Translational Medicine, State Key Laboratory of Radiation Medicine and Protection, Key Laboratory of Stem Cells and Medical Biomaterials of Jiangsu Province, Soochow University Medical College, Suzhou, China.
Yanan LiThe First Affiliated Hospital of Soochow University, Institutes for Translational Medicine, State Key Laboratory of Radiation Medicine and Protection, Key Laboratory of Stem Cells and Medical Biomaterials of Jiangsu Province, Soochow University Medical College, Suzhou, China.
Rui LiuThe First Affiliated Hospital of Soochow University, Institutes for Translational Medicine, State Key Laboratory of Radiation Medicine and Protection, Key Laboratory of Stem Cells and Medical Biomaterials of Jiangsu Province, Soochow University Medical College, Suzhou, China.
Chenchang XuThe First Affiliated Hospital of Soochow University, Institutes for Translational Medicine, State Key Laboratory of Radiation Medicine and Protection, Key Laboratory of Stem Cells and Medical Biomaterials of Jiangsu Province, Soochow University Medical College, Suzhou, China.
Xiaoren ZhangKey Laboratory of Tissue Microenvironment and Tumor, Institute of Health Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China.
Baochi LiuDepartment of Surgery, Shanghai Public Health Clinical Center Fudan University, Shanghai, China.
Luowei WangDepartment of Gastroenterology, Changhai Hospital, Second Military Medical University, Shanghai, China. wangluoweimd@126.com.
Changshun ShaoThe First Affiliated Hospital of Soochow University, Institutes for Translational Medicine, State Key Laboratory of Radiation Medicine and Protection, Key Laboratory of Stem Cells and Medical Biomaterials of Jiangsu Province, Soochow University Medical College, Suzhou, China. shaoc@suda.edu.cn.ORCID http://orcid.org/0000-0003-2618-9342
Ying WangKey Laboratory of Tissue Microenvironment and Tumor, Institute of Health Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China. yingwang@sibs.ac.cn.
Yufang ShiThe First Affiliated Hospital of Soochow University, Institutes for Translational Medicine, State Key Laboratory of Radiation Medicine and Protection, Key Laboratory of Stem Cells and Medical Biomaterials of Jiangsu Province, Soochow University Medical College, Suzhou, China. yfshi@suda.edu.cn.ORCID http://orcid.org/0000-0001-9716-2126
Soochow University · CNShanghai Institutes for Biological Sciences · CNSecond Military Medical University · CNShanghai Institute of Nutrition and Health · CNShanghai Public Health Clinical Center · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The reconstitution of the T-cell repertoire and quantity is a major challenge in the clinical management of HIV infection/AIDS, cancer, and aging-associated diseases. We previously showed that autologous bone marrow transfusion (BMT) via the hepatic portal vein could effectively restore CD4

Indexed as

Cell DifferentiationAdaptor Proteins, Signal TransducingAnimalsBone Marrow TransplantationCalcium-Binding ProteinsCarbon TetrachlorideCells, CulturedChemokine CXCL12DNA-Binding ProteinsFibroblastsHematopoietic Stem CellsHepatocytesHIV InfectionsHumansLiverLiver CirrhosisAdaptor Proteins, Signal TransducingCalcium-Binding ProteinsCarbon TetrachlorideChemokine CXCL12Cxcl12 protein, mouseDLL4 protein, mouseDNA-Binding ProteinsNF-kappa BRag2 protein, mouseTumor Necrosis Factor-alpha

Identifiers

PMID31165736
PMCPMC6549170
OpenAlexW2948791255

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.