Evidence map›Paper›PMID 31165658›Full record

ArticleJournal of the American Heart Association2019

Adverse Events After Atherectomy: Analyzing Long-Term Outcomes of Endovascular Lower Extremity Revascularization Techniques.

Niveditta Ramkumar, Pablo Martinez-Camblor, Jesse A Columbo, Nicholas H Osborne, Philip P Goodney, A James O'Malley

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 59 citations in OpenAlex.

  1. Atherectomy for peripheral arterial disease.The Cochrane database of systematic reviews · 2020
    Pooled it
  2. Article
  3. Article
  4. Atherectomy With Multimodal Embolic Protection for Severely Calcified Femoropopliteal Lesions.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2026
    Article
  5. Observational
  6. Article
  7. Article
  8. Validation ofCirculation. Cardiovascular quality and outcomes · 2025
    Article
  9. Editor's Choice - Infrapopliteal Peripheral Vascular Interventions for Claudication are Performed Frequently in the USA and Are Associated with Poor Long Term Outcomes.European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery · 2025
    Article
  10. Article
  11. Article
  12. Device regulation and surveillance in vascular care: Challenges and opportunities.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2024
    Review
  13. Article
  14. Article
  15. Outcomes of atherectomy in patients undergoing lower extremity revascularisation.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2023
    Article
  16. Article
  17. Long-term outcomes of peripheral atherectomy for femoropopliteal endovascular interventions.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2023
    Article
  18. Review
  19. Atherectomy Overuse: Do Policy Solutions Exist?Journal of the American Heart Association · 2022
    Article
  20. Assessment of Patterns of Atherectomy Use.Journal of the American Heart Association · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Niveditta Ramkumar1 The Dartmouth Institute for Health Policy and Clinical Practice Lebanon NH.
Pablo Martinez-Camblor1 The Dartmouth Institute for Health Policy and Clinical Practice Lebanon NH.
Jesse A Columbo2 Section of Vascular Surgery Department of Surgery Dartmouth-Hitchcock Medical Center Lebanon NH.
Nicholas H Osborne3 Section of Vascular Surgery University of Michigan Medical School Ann Arbor MI.
Philip P Goodney1 The Dartmouth Institute for Health Policy and Clinical Practice Lebanon NH.
A James O'Malley1 The Dartmouth Institute for Health Policy and Clinical Practice Lebanon NH.
Dartmouth–Hitchcock Medical Center · USDartmouth Institute for Health Policy and Clinical Practice · USUniversity of Michigan–Ann Arbor · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background The long-term effectiveness of atherectomy treatment for peripheral arterial disease is unknown. We studied 5-year clinical outcomes by endovascular treatment type among patients with peripheral arterial disease. Methods and Results We queried the Medicare-linked VQI (Vascular Quality Initiative) registry for endovascular interventions from 2010 to 2015. The exposure was treatment type: atherectomy (with or without percutaneous transluminal angioplasty [ PTA] ), stent (with or without PTA ), or PTA alone. The outcomes were major amputation, any amputation, and major adverse limb event (major amputation or any reintervention). We used the center-specific proportions of atherectomy procedures performed in the 12 months before a patient's procedure as the instruments to perform an instrumental-variable Cox model analysis. Among 16 838 eligible patients (median follow-up: 1.3-1.5 years), 11% underwent atherectomy, 40% received PTA alone, and 49% underwent stenting. Patients receiving atherectomy commonly underwent femoropopliteal artery treatment (atherectomy: 65%; PTA : 49%; stenting: 43%; P<0.001) and had worse disease severity (Trans-Atlantic Inter-Society Consensus score [TASC] B and greater; atherectomy: 77%; PTA : 68%; stenting: 67%; P<0.001). The 5-year rate of major adverse limb events was 38% in patients receiving atherectomy versus 33% for PTA and 32% for stenting (log rank P<0.001). Controlling for unmeasured confounding using instrumental-variable analysis, patients treated with atherectomy experienced outcomes similar to those of patients treated with PTA , except for a higher risk of any amputation (hazard ratio: 1.51; 95% CI , 1.08-2.13). However, compared with stenting, atherectomy patients had a higher risk of major amputation (hazard ratio: 3.66; 95% CI , 1.72-7.81), any amputation (hazard ratio: 2.73; 95% CI , 1.60-4.76), and major adverse limb event (hazard ratio: 1.61; 95% CI , 1.10-2.38). Conclusions Atherectomy is used to treat severe femoropopliteal and tibial peripheral arterial disease even though long-term adverse outcomes occur more frequently after this treatment modality.

Indexed as

Endovascular ProceduresFemoral ArteryPopliteal ArteryAgedAged, 80 and overAmputation, SurgicalAtherectomyCohort StudiesFemaleHumansLower ExtremityMaleMiddle AgedPeripheral Arterial DiseasePostoperative ComplicationsTime Factorsangioplastyatherectomyoutcomesperipheral artery diseasestent

Identifiers

PMID31165658
PMCPMC6645635
OpenAlexW2953158091

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.