ArticleInfection2019
AE hepatic lesions: correlation between calcifications at CT and FDG-PET/CT metabolic activity.
Article in Infection, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 45 citations in OpenAlex.
- Correlation between imaging features and rEm18 antibodies in alveolar echinococcosis: results from a multicenter study in France.Parasite (Paris, France) · 2025Trial
- Diagnosis of hepatic alveolar echinococcosis:18F-FDG-PET activity compared to the Echinococcus multilocularis Ulm Ultrasound Classification.Nuklearmedizin. Nuclear medicine · 2026Article
- The initial stage of alveolar echinococcosis is a diagnostic challenge: a case report.Journal of medical case reports · 2025Article
- The value of nomogram analysis in predicting pulmonary metastasis in hepatic alveolar echinococcosis.Scientific reports · 2025Article
- CT imaging features and diagnostic algorithm for hepatic cystic echinococcosis.Scientific reports · 2025Article
- CT-based radiomics models using intralesional and different perilesional signatures in predicting the microvascular density of hepatic alveolar echinococcosis.BMC medical imaging · 2025Article
- Advances in Novel Diagnostic Techniques for Alveolar Echinococcosis.Diagnostics (Basel, Switzerland) · 2025Review
- Pictorial review of hepatic echinococcosis: Ultrasound imaging and differential diagnosis.World journal of gastroenterology · 2024Review
- Clinical value of the semi-quantitative parameters ofBMC medical imaging · 2024Article
- Rare recurrent brain alveolar echinococcosis complicated by systemic multiorgan infection-a case description.Quantitative imaging in medicine and surgery · 2023Article
- LncRNA Regulation Mechanism in Hepatic Alveolar Echinococcosis with Nanosecond Pulse.Acta parasitologica · 2023Article
- Stage-Oriented CT Classification and Intermodal Evolution Model in Hepatic Alveolar Echinococcosis.RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin · 2022Article
- Role of the radiologist in the diagnosis and management of the two forms of hepatic echinococcosis.Insights into imaging · 2022Review
- Long-term follow-up of liver alveolar echinococcosis using echinococcosis multilocularis ultrasound classification.World journal of gastroenterology · 2021Article
- Quantitative evaluation of range and metabolic activity of hepatic alveolar echinococcosis lesion microenvironment using PET/CT and multi-site sampling method.BMC infectious diseases · 2021Article
- Kodama-XUUB: an informative classification for alveolar echinococcosis hepatic lesions on magnetic resonance imaging.Parasite (Paris, France) · 2021Article
- Hepatic alveolar echinococcosis: correlation between computed tomography morphology and inflammatory activity in positron emission tomography.Scientific reports · 2020Article
- Hepatic alveolar echinococcosis: Comparative computed tomography study between two Chinese and two European centres.Food and waterborne parasitology · 2020Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo correlate the presence of calcifications in alveolar echinococcosis (AE) hepatic lesions to the metabolic activity in 18 fluorodeoxyglucose positron emission tomography combined with computed tomography (FDG-PET/CT).
methodsOur institutional review board approved this study. 61 patients (29 women, 32 men, aged from 15 to 86 years) were included in the study. Images of FDG-PET/CT were interpreted by two independent nuclear medicine physicians. AE hepatic lesions were classified as AE lesions with or without hypermetabolic activity. The presence of calcifications was assessed on unenhanced CT scans by two independent radiologists blinded with regard to the metabolic activity of the AE hepatic lesions. Every single calcification the size of which was < 3 mm and non-measurable calcifications which were forming areas with a powdery appearance were considered as microcalcifications. All other types of calcifications were reported as macrocalcifications. Statistical analysis was performed and p value < 0.05 was considered as statistically significant.
resultsMicrocalcifications and macrocalcifications were present at CT in 95% (58/61) AE hepatic lesions and 43% (26/61) AE hepatic lesions, respectively. Hypermetabolic activity was present at FDG-PET/CT in 93% (57/61) AE hepatic lesions. 98% (56/57) of the AE hepatic lesions presenting with hypermetabolic activity at FDG-PET/CT showed microcalcifications at CT (p = 0.01) when only 40% (23/57) showed macrocalcifications at CT (p = 0.3). 100% (23/23) of the AE hepatic lesions with hypermetabolic activity at FDG-PET/CT and macrocalcifications at CT showed also microcalcifications at CT.
conclusionsHypermetabolic activity of AE hepatic lesions at FDG-PET/CT is strongly correlated to the presence of microcalcifications at CT, independently of the presence of macrocalcifications.
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