ArticleCognitive, affective & behavioral neuroscience2019
Negative affect moderates the effect of social rejection on frontal and anterior cingulate cortex activation in borderline personality disorder.
Article in Cognitive, affective & behavioral neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.
- Parsing variability in borderline personality disorder: a meta-analysis of neuroimaging studies.Translational psychiatry · 2021Pooled it
- Neural correlates of social cognition in BPD: a review of MRI evidence.European archives of psychiatry and clinical neuroscience · 2026Review
- Reduced activation in empathy core regions during observation of social interactions in patients with borderline personality disorder: an fMRI-study.Translational psychiatry · 2026Article
- Preschool Big Five Personality Traits Predict Childhood Peer Relationships and BPD but Not MDD in Late Adolescence.Personality and mental health · 2025Article
- Brain Activation for Social Cognition and Emotion Processing Tasks in Borderline Personality Disorder: A Meta-Analysis of Neuroimaging Studies.Brain sciences · 2024Review
- Social exclusion: differences in neural mechanisms underlying direct versus vicarious experience.Frontiers in psychology · 2024Article
- Depression with comorbid borderline personality disorder - could ketamine be a treatment catalyst?Frontiers in psychiatry · 2024Review
- Neural correlates of social exclusion and overinclusion in patients with borderline personality disorder: an fMRI study.Borderline personality disorder and emotion dysregulation · 2023Article
- Rejection Distress Suppresses Medial Prefrontal Cortex in Borderline Personality Disorder.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2023Article
- Abnormal Brain Circuits Characterize Borderline Personality and Mediate the Relationship between Childhood Traumas and Symptoms: A mCCA+jICA and Random Forest Approach.Sensors (Basel, Switzerland) · 2023Article
- Article
- Borderline Personality Disorder: Updates in a Postpandemic World.Focus (American Psychiatric Publishing) · 2022Review
- MDMA-Assisted Psychotherapy for Borderline Personality Disorder.Focus (American Psychiatric Publishing) · 2022Review
- Social exclusion increases the executive function of attention networks.Scientific reports · 2021Article
- Can neuroscience help to understand narcissism? A systematic review of an emerging field.Personality neuroscience · 2021Review
- Brain responses to social feedback in internalizing disorders: A comprehensive review.Neuroscience and biobehavioral reviews · 2020Review
- The Pain Paradox of Borderline Personality and Total Knee Arthroplasty (TKA): Recruiting Borderline Personality Organization to Predict the One-Year Postoperative Outcome.Journal of pain research · 2020Article
- Altered regional homogeneity and its association with cognitive function in adolescents with borderline personality disorder.Journal of psychiatry & neuroscience : JPNArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Patients with borderline personality disorder (BPD) have a heightened sensitivity to social exclusion. Experimental manipulations have produced inconsistent findings and suggested that baseline negative affect (NA) might influence the experience of exclusion. We administered a standardized social exclusion protocol (Cyberball paradigm) in BPD (n = 39) and age-matched and sex-matched healthy controls (n = 29) to investigate the association of NA on social exclusion and activation in brain regions previously implicated in this paradigm. Compared with controls, patients with BPD showed higher activation during social exclusion in the anterior cingulate cortex (ACC), the medial prefrontal cortex (mPFC), and in the right precuneus. Prescan NA ratings were associated with higher brain activation in the ACC and mPFC over all conditions, and post hoc t tests revealed that differences between the groups were only significant when controlling for NA. Brain activation during exclusion was correlated with NA separately for each group. Only BPD patients showed a significant association of NA and exclusion related precuneus activation (r = .52 p = .001). Additionally, BPD patients experienced less feelings of belonging compared with a healthy control (HC) group during inclusion and exclusion, although they estimated their ball possessions significantly higher than did the HC. These findings suggest that baseline NA has a crucial impact on Cyberball-related brain activation. The results underscore the importance of considering levels of NA in social exclusion protocols for participants high in this trait.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.