ArticleJournal of nephrology2019
Stone composition and vascular calcifications in patients with nephrolithiasis.
Article in Journal of nephrology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 25 citations in OpenAlex.
- Effect of water composition and timing of ingestion on urinary lithogenic profile in healthy volunteers: a randomized crossover trial.Journal of nephrology · 2021Trial
- Oxidative stress, inflammation and kidney stones.Urolithiasis · 2025Article
- Between a Rock and a Short Place-The Impact of Nephrolithiasis on Skeletal Growth and Development Across the Lifespan.Current osteoporosis reports · 2024Review
- Association of Red Blood Cell Distribution Width to Albumin Ratio With the Prevalence of Kidney Stones Among the General Adult Population.Immunity, inflammation and disease · 2024Article
- Vascular calcification in kidney stone formers: the impact of age and stone composition.Urolithiasis · 2024Article
- Urinary stone analysis and clinical characteristics of 496 patients in Taiwan.Scientific reports · 2024Article
- The Association between Aortic Calcification Index and Urinary Stones: A Cross-Sectional Study.Journal of clinical medicine · 2022Article
- Nephrolithiasis: A Red Flag for Cardiovascular Risk.Journal of clinical medicine · 2022Review
- Association between aortic calcification and the presence of kidney stones: calcium oxalate calculi in focus.International urology and nephrology · 2022Article
- Vascular Calcification Is Associated with Fetuin-A and Cortical Bone Porosity in Stone Formers.Journal of personalized medicine · 2022Article
- Urinary metabolic profile and stone composition in kidney stone formers with and without heart disease.Journal of nephrology · 2022Article
- Calcium and Vitamin D Supplementation and Their Association with Kidney Stone Disease: A Narrative Review.Nutrients · 2021Review
- The relationship between vascular calcifications and urolithiasis in a large, multiethnic patient population.Urolithiasis · 2021Article
- Practice patterns of kidney stone management across European and non-European centers: an in-depth investigation from the European Renal Stone Network (ERSN).Journal of nephrology · 2021Article
- Editorial: Immunity and Inflammatory Response in Kidney Stone Disease.Frontiers in immunology · 2021Article
- Risk of Kidney Stones: Influence of Dietary Factors, Dietary Patterns, and Vegetarian-Vegan Diets.Nutrients · 2020Review
- ChlorthalidoneAnnals of translational medicine · 2019Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Kidney stone disease is associated with cardiovascular outcomes; it is unclear whether stone composition is associated with differential cardiovascular risk. To analyze such association, we performed a cross-sectional study in which data were collected for patients who underwent at least one stone composition analysis from January 01 2015 to May 30 2018. The original dataset was linked with the imaging database to identify those patients with at least one abdominal CT scan examination during the period of interest. In total, 180 patients were included. The outcome of interest was the presence of any abdominal aortic calcifications (AAC) computed from CT scans. There were 108 (60.0%) patients with AAC. Calcium phosphate content was associated directly with eGFR, inversely with age, and was higher among females. Uric acid content was associated directly with age and inversely with eGFR, was higher among males, patients with diabetes and high blood pressure. After adjustment for age and gender, there was a significant association between calcium phosphate content and AAC (OR 1.25, 95% CI 1.00, 1.56, p = 0.045). No interaction by gender was found between calcium phosphate content and AAC (p = 0.84). In conclusion, we demonstrated a significant direct association of AAC and the amount of calcium phosphate was found, suggesting an increased cardiovascular risk. Our study suggests that some subtypes of kidney stone disease deserve a closer cardiovascular risk assessment.
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