Evidence map›Paper›PMID 31165309›Full record

ArticleInternational archives of occupational and environmental health2019

Inflammatory and coagulatory markers and exposure to different size fractions of particle mass, number and surface area air concentrations in Swedish iron foundries, in particular respirable quartz.

Håkan Westberg, Alexander Hedbrant, Alexander Persson, Ing-Liss Bryngelsson, Anders Johansson, Annette Ericsson, Bengt Sjögren, Leo Stockfelt, Eva Särndahl, Lena Andersson

Open access · hybridAbstract read
In one paragraph

Article in International archives of occupational and environmental health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 20 citations in OpenAlex.

  1. The prevalence of respiratory symptoms and diseases and declined lung function among foundry workers.Journal of occupational medicine and toxicology (London, England) · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Håkan WestbergDepartment of Occupational and Environmental Medicine, Faculty of Medicine and Health, Örebro University, 70182, Örebro, Sweden. hakan.westberg@regionorebrolan.se.
Alexander HedbrantDepartment of Medical Sciences, School of Medicine and Health, Örebro University, 701 82, Örebro, Sweden.
Alexander PerssonDepartment of Medical Sciences, School of Medicine and Health, Örebro University, 701 82, Örebro, Sweden.
Ing-Liss BryngelssonDepartment of Occupational and Environmental Medicine, Faculty of Medicine and Health, Örebro University, 70182, Örebro, Sweden.
Anders JohanssonDepartment of Occupational and Environmental Medicine, Faculty of Medicine and Health, Örebro University, 70182, Örebro, Sweden.
Annette EricssonDepartment of Occupational and Environmental Medicine, Faculty of Medicine and Health, Örebro University, 70182, Örebro, Sweden.
Bengt SjögrenWork Environment Toxicology, Institute of Environmental Medicine, Karolinska Institutet, 171 77, Stockholm, Sweden.
Leo StockfeltDepartment of Occupational and Environmental Medicine, University of Gothenburg, PB 414, 405 30, Göteborg, Sweden.
Eva SärndahlDepartment of Medical Sciences, School of Medicine and Health, Örebro University, 701 82, Örebro, Sweden.
Lena AnderssonDepartment of Occupational and Environmental Medicine, Faculty of Medicine and Health, Örebro University, 70182, Örebro, Sweden.
Örebro University · SEKarolinska Institutet · SEÖrebro University Hospital · SEUniversity of Gothenburg · SE

Funding

Knowledge Foundation 20150036Örebro University Strategic grant ORU 2.2.1-4060/2013Swedish Research Council for Health, Working Life and Welfare (FORTE) 2014-0802
6 · The paper itself

Abstract

purposeTo study the relationship between inhalation of airborne particles and quartz in Swedish iron foundries and markers of inflammation and coagulation in blood.

methodsPersonal sampling of respirable dust and quartz was performed for 85 subjects in three Swedish iron foundries. Stationary measurements were used to study the concentrations of respirable dust and quartz, inhalable and total dust, PM10 and PM2.5, as well as the particle surface area and the particle number concentrations. Markers of inflammation, namely interleukins (IL-1β, IL-6, IL-8, IL-10 and IL-12), C-reactive protein, and serum amyloid A (SAA) were measured in plasma or serum, together with markers of coagulation including fibrinogen, factor VIII (FVIII), von Willebrand factor and D-dimer. Complete sampling was performed on the second or third day of a working week after a work-free weekend, and follow-up samples were collected 2 days later. A mixed model analysis was performed including sex, age, smoking, infections, blood group, sampling day and BMI as covariates.

resultsThe average 8-h time-weighted average air concentrations of respirable dust and quartz were 0.85 mg/m

conclusionsThese observed relationships between particle exposure and inflammatory markers may indicate an increased risk of cardiovascular disease among foundry workers with high particulate exposure.

Indexed as

Air Pollutants, OccupationalBiomarkersC-Reactive ProteinDustEnvironmental MonitoringHumansInhalation ExposureIronMetallurgyOccupational ExposureQuartzSerum Amyloid A ProteinSilicon DioxideSwedenAir Pollutants, OccupationalBiomarkersC-Reactive ProteinDustIronQuartzSerum Amyloid A ProteinSilicon DioxideInflammatory markersIron foundriesParticle massParticle numberParticle surface areaRespirable quartz

Identifiers

PMID31165309
PMCPMC6814634
OpenAlexW2948920967

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.