Evidence map›Paper›PMID 31165279›Full record

ArticlePharmaceutical research2019

Proton Oriented-"Smart Depot" for Responsive Release of Ca

Jiwei Liu, Yan Xu, Yonglu Wang, Hao Ren, Zhengjie Meng, Kuntang Liu, Zhe Liu, He Huang, Xueming Li

Abstract read
PubMed Publisher
In one paragraph

Article in Pharmaceutical research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Jiwei LiuSchool of Pharmaceutical Science, Nanjing Tech University, No. 30 Puzhu South Road, Nanjing, 211816, China.
Yan XuSchool of Pharmaceutical Science, Nanjing Tech University, No. 30 Puzhu South Road, Nanjing, 211816, China.
Yonglu WangSchool of Pharmaceutical Science, Nanjing Tech University, No. 30 Puzhu South Road, Nanjing, 211816, China.
Hao RenSchool of Pharmaceutical Science, Nanjing Tech University, No. 30 Puzhu South Road, Nanjing, 211816, China.
Zhengjie MengSchool of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, No. 30 Puzhu South Road, Nanjing, 211816, China.
Kuntang LiuSchool of Pharmaceutical Science, Nanjing Tech University, No. 30 Puzhu South Road, Nanjing, 211816, China.
Zhe LiuSchool of Pharmaceutical Science, Nanjing Tech University, No. 30 Puzhu South Road, Nanjing, 211816, China.
He HuangSchool of Pharmaceutical Science, Nanjing Tech University, No. 30 Puzhu South Road, Nanjing, 211816, China. huangh@njtech.edu.cn.
Xueming LiSchool of Pharmaceutical Science, Nanjing Tech University, No. 30 Puzhu South Road, Nanjing, 211816, China. xuemingli@njtech.edu.cn.
Nanjing Tech University · CN

Funding

National Natural Science Foundation of China Nos. 21476111,21776136National Natural Science Foundation of China Nos.81803439
6 · The paper itself

Abstract

purposeThe purpose of this study was to characterize and detail the mechanism of a smart Ca

methodsThe octreotide acetate release and acylation kinetics were analyzed by RP-HPLC. Changes of Ca

resultsBefore and after microspheres formulation, the property and effectiveness of Ca

conclusionsWith the presence of the smart Ca

Indexed as

MicrospheresAcylationAdsorptionCalciumCalcium PhosphatesCations, DivalentDrug CarriersDrug LiberationHydrogen-Ion ConcentrationKineticsOctreotidePeptidesPolylactic Acid-Polyglycolic Acid CopolymerProtonsSolubilityStatic ElectricityCalciumCalcium PhosphatesCations, DivalentDrug CarriersOctreotidePeptidesPolylactic Acid-Polyglycolic Acid CopolymerProtonsWaterCa3(PO4)2high encapsulationlong-term inhibitionPeptide acylationsmart depot

Identifiers

PMID31165279
OpenAlexW2948385762

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.