Evidence map›Paper›PMID 31165072›Full record

ArticleFrontiers in nutrition2019

Impact of the Food Additive Titanium Dioxide (E171) on Gut Microbiota-Host Interaction.

Gabriela Pinget, Jian Tan, Bartlomiej Janac, Nadeem O Kaakoush, Alexandra Sophie Angelatos, John O'Sullivan, Yen Chin Koay, Frederic Sierro, Joel Davis, Shiva Kamini Divakarla and 5 more

Erratum issuedOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in nutrition, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 59 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed, 2 pooled it
7.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 2 syntheses or guidelines pooled it, 130 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Review
  5. Investigation of the Effect of TiOAnimals : an open access journal from MDPI · 2026
    Article
  6. Food-grade TiOJournal of nanobiotechnology · 2026
    Article
  7. Review
  8. Review
  9. Review
  10. Article
  11. Food Additives: Emerging Detrimental Roles on Gut Health.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Review
  12. Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. The Recommendation of the Mediterranean-styled Japanese Diet for Healthy Longevity.Endocrine, metabolic & immune disorders drug targets · 2024
    Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 1 country.

Gabriela PingetThe Charles Perkins Centre, The University of Sydney, Sydney, NSW, Australia.
Jian TanThe Charles Perkins Centre, The University of Sydney, Sydney, NSW, Australia.
Bartlomiej JanacThe Charles Perkins Centre, The University of Sydney, Sydney, NSW, Australia.
Nadeem O KaakoushSchool of Medical Sciences, University of New South Wales, Sydney, NSW, Australia.
Alexandra Sophie AngelatosThe Charles Perkins Centre, The University of Sydney, Sydney, NSW, Australia.
John O'SullivanDepartment of Cardiology, Charles Perkins Centre, Royal Prince Alfred Hospital, Heart Research Institute, University of Sydney, Sydney, NSW, Australia.
Yen Chin KoayDepartment of Cardiology, Charles Perkins Centre, Royal Prince Alfred Hospital, Heart Research Institute, University of Sydney, Sydney, NSW, Australia.
Frederic SierroHuman Health, Nuclear Science & Technology and Landmark Infrastructure (NSTLI), Australian Nuclear Science and Technology Organisation, Sydney, NSW, Australia.
Joel DavisHuman Health, Nuclear Science & Technology and Landmark Infrastructure (NSTLI), Australian Nuclear Science and Technology Organisation, Sydney, NSW, Australia.
Shiva Kamini DivakarlaSydney Nano Institute, The University of Sydney, Sydney, NSW, Australia.
Dipesh KhanalSydney Nano Institute, The University of Sydney, Sydney, NSW, Australia.
Robert J MooreSchool of Science, RMIT University, Bundoora, VIC, Australia.
Dragana StanleySchool of Health, Medical and Applied Sciences, Central Queensland University, Rockhampton, QLD, Australia.
Wojciech ChrzanowskiSydney Nano Institute, The University of Sydney, Sydney, NSW, Australia.
Laurence MaciaThe Charles Perkins Centre, The University of Sydney, Sydney, NSW, Australia.
University of Sydney · AUAustralian Nuclear Science and Technology Organisation · AUCentral Queensland University · AURMIT University · AUUNSW Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The interaction between gut microbiota and host plays a central role in health. Dysbiosis, detrimental changes in gut microbiota and inflammation have been reported in non-communicable diseases. While diet has a profound impact on gut microbiota composition and function, the role of food additives such as titanium dioxide (TiO

Indexed as

biofilmgut microbiotaimmune cellsinflammationtitanium dioxide

Identifiers

PMID31165072
PMCPMC6534185
OpenAlexW2946252026

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.