Evidence map›Paper›PMID 31165030›Full record

ArticleBeilstein journal of nanotechnology2019

Enhanced inhibition of influenza virus infection by peptide-noble-metal nanoparticle conjugates.

Zaid K Alghrair, David G Fernig, Bahram Ebrahimi

Open access · diamondAbstract read
In one paragraph

Article in Beilstein journal of nanotechnology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 51 citations in OpenAlex.

  1. Review
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  7. Article
  8. Nanoparticles in clinical trials of COVID-19: An update.International journal of surgery (London, England) · 2022
    Review
  9. Metallic Structures: Effective Agents to Fight Pathogenic Microorganisms.International journal of molecular sciences · 2022
    Review
  10. Article
  11. Review
  12. Review
  13. Silver nanoparticles as a potential treatment against SARS-CoV-2: A review.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology · 2021
    Review
  14. Review
  15. Article
  16. Nanotechnology-based antiviral therapeutics.Drug delivery and translational research · 2021
    Review
  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 2 countries.

Zaid K AlghrairDepartment of Biochemistry Institute of Integrative Biology, Biosciences Building, Crown Street, University of Liverpool, Liverpool, L69 7ZB, UK.ORCID 0000-0002-3600-8245
David G FernigDepartment of Biochemistry Institute of Integrative Biology, Biosciences Building, Crown Street, University of Liverpool, Liverpool, L69 7ZB, UK.ORCID 0000-0003-4875-4293
Bahram EbrahimiDepartment of Functional and Comparative Genomics, Institute of Integrative Biology, Biosciences Building, Crown Street, University of Liverpool, Liverpool, L69 7ZB, UK.ORCID 0000-0002-8758-4592
University of Liverpool · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The influenza ("flu") type-A virus is a major medical and veterinary health concern and causes global pandemics. The peptide "FluPep" is an established inhibitor of influenza virus infectivity in model systems. We have explored the potential for noble-metal nanoparticle conjugates of FluPep to enhance its antiviral activity and to determine their potential as a delivery platform for FluPep. FluPep ligand is FluPep extended at its N-terminus with the sequence CVVVTAAA, to allow for its incorporation into a mixed-matrix ligand shell of a peptidol and an alkanethiol ethylene glycol consisting of 70% CVVVTol and 30% HS(CH

Indexed as

antiviral peptidesgold nanoparticlesinfluenza viruslytic infectionsilver nanoparticles

Identifiers

PMID31165030
PMCPMC6541353
OpenAlexW2952759529

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.