Evidence map›Paper›PMID 31164941›Full record

ArticleBeilstein journal of organic chemistry2019

Novel (2-amino-4-arylimidazolyl)propanoic acids and pyrrolo[1,2-

Victoria V Lipson, Tetiana L Pavlovska, Nataliya V Svetlichnaya, Anna A Poryvai, Nikolay Yu Gorobets, Erik V Van der Eycken, Irina S Konovalova, Svetlana V Shiskina, Alexander V Borisov, Vladimir I Musatov and 1 more

Open access · diamondAbstract read
In one paragraph

Article in Beilstein journal of organic chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 58% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 6 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 3 countries.

Victoria V LipsonSSI "Institute for Single Crystals" of National Academy of Sciences of Ukraine, Nauky Ave. 60, Kharkiv 61074, Ukraine.
Tetiana L PavlovskaSSI "Institute for Single Crystals" of National Academy of Sciences of Ukraine, Nauky Ave. 60, Kharkiv 61074, Ukraine.
Nataliya V SvetlichnayaAntidiabetic Drug Laboratory, SI "V.Ya. Danilevsky Institute for Endocrine Pathology Problems", Academy of Medical Sciences of Ukraine, 10, Alchevskih St., Kharkiv 61002, Ukraine.
Anna A PoryvaiChemistry Department, V.N. Karazin Kharkov National University, Kharkov 61022, Ukraine.
Nikolay Yu GorobetsSSI "Institute for Single Crystals" of National Academy of Sciences of Ukraine, Nauky Ave. 60, Kharkiv 61074, Ukraine.
Erik V Van der EyckenLaboratory for Organic & Microwave-Assisted Chemistry (LOMAC), Katholieke Universiteit Leuven, Celestijnenlaan 200F, B-3001 Leuven, Belgium.
Irina S KonovalovaSSI "Institute for Single Crystals" of National Academy of Sciences of Ukraine, Nauky Ave. 60, Kharkiv 61074, Ukraine.ORCID 0000-0001-6245-6642
Svetlana V ShiskinaSSI "Institute for Single Crystals" of National Academy of Sciences of Ukraine, Nauky Ave. 60, Kharkiv 61074, Ukraine.ORCID 0000-0002-3946-1061
Alexander V BorisovEnamine Ltd., 23 Chervonotkats'ka str., Kyiv 01003, Ukraine.
Vladimir I MusatovSSI "Institute for Single Crystals" of National Academy of Sciences of Ukraine, Nauky Ave. 60, Kharkiv 61074, Ukraine.
Alexander V MazepaA.V. Bogatsky physico-chemical institute of the National Academy of Sciences of Ukraine, 86, Lustdorfskaya doroga, 65080, Odessa, Ukraine.
National Academy of Sciences of Ukraine · UAEnamine (Ukraine) · UANational Academy of Medical Sciences of Ukraine · UAPeoples' Friendship University of Russia · RUV. N. Karazin Kharkiv National University · UA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The unexpectedly uncatalyzed reaction between 2-amino-4-arylimidazoles, aromatic aldehydes and Meldrum's acid has selectively led to the corresponding Knoevenagel-Michael adducts containing a free amino group in the imidazole fragment. The adducts derived from Meldrum's acid have been smoothly converted into 1,7-diaryl-3-amino-6,7-dihydro-5

Indexed as

2-amino-4-arylimidazole(2-amino-4-arylimidazolyl)propanoic acid3,3’-spirooxindolesisatinMeldrum’s acidmulticomponent reactionspyrrolo[1,2-c]imidazole

Identifiers

PMID31164941
PMCPMC6541323
OpenAlexW2944790764

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.