Evidence map›Paper›PMID 31164889›Full record

ArticleFrontiers in immunology2019

Investigation of Oligoclonal IgG Bands in Tear Fluid of Multiple Sclerosis Patients.

Martin W Hümmert, Ulrich Wurster, Lena Bönig, Philipp Schwenkenbecher, Kurt-Wolfram Sühs, Sascha Alvermann, Stefan Gingele, Thomas Skripuletz, Martin Stangel

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Towards primary prevention of multiple sclerosis.Nature reviews. Neurology · 2026
    Review
  3. Tear fluid proteomics: a comparative study of DIA and DDA mass spectrometry.Journal of mass spectrometry and advances in the clinical lab · 2025
    Article
  4. Tear fluid participates in systemic immunity.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2025
    Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Experimental laboratory biomarkers in multiple sclerosis.Wiener medizinische Wochenschrift (1946) · 2022
    Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Martin W HümmertDepartement of Neurology, Clinical Neuroimmunology and Neurochemistry, Hannover Medical School, Hannover, Germany.
Ulrich WursterDepartement of Neurology, Clinical Neuroimmunology and Neurochemistry, Hannover Medical School, Hannover, Germany.
Lena BönigDepartement of Neurology, Clinical Neuroimmunology and Neurochemistry, Hannover Medical School, Hannover, Germany.
Philipp SchwenkenbecherDepartement of Neurology, Clinical Neuroimmunology and Neurochemistry, Hannover Medical School, Hannover, Germany.
Kurt-Wolfram SühsDepartement of Neurology, Clinical Neuroimmunology and Neurochemistry, Hannover Medical School, Hannover, Germany.
Sascha AlvermannDepartement of Neurology, Clinical Neuroimmunology and Neurochemistry, Hannover Medical School, Hannover, Germany.
Stefan GingeleDepartement of Neurology, Clinical Neuroimmunology and Neurochemistry, Hannover Medical School, Hannover, Germany.
Thomas SkripuletzDepartement of Neurology, Clinical Neuroimmunology and Neurochemistry, Hannover Medical School, Hannover, Germany.
Martin StangelDepartement of Neurology, Clinical Neuroimmunology and Neurochemistry, Hannover Medical School, Hannover, Germany.
Medizinische Hochschule Hannover · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdolescentAdultAgedBiomarkersCerebrospinal FluidEvoked Potentials, VisualFemaleHumansImmunoglobulin GMaleMiddle AgedMultiple SclerosisOligoclonal BandsOptic NeuritisReproducibility of ResultsSerumBiomarkersImmunoglobulin GOligoclonal Bandscerebrospinal fluidCSFMSmultiple scleroisoligoclonal band (OCB)tear fluidtears

Identifiers

PMID31164889
PMCPMC6534077
OpenAlexW2946811164

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.