Evidence map›Paper›PMID 31164888›Full record

ReviewFrontiers in immunology2019

Vascular Smooth Muscle Cells Contribute to Atherosclerosis Immunity.

Desheng Hu, Changjun Yin, Shanshan Luo, Andreas J R Habenicht, Sarajo K Mohanta

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 98 citations in OpenAlex.

  1. Review
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  3. Article
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  6. Sjogren's Disease and Elevated Cardiovascular Risk: Mechanisms and Treatment.Journal of cardiovascular development and disease · 2025
    Review
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Insights from Murine Studies on the Site Specificity of Atherosclerosis.International journal of molecular sciences · 2024
    Review
  13. Review
  14. Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. Cardiovascular Brain Circuits.Circulation research · 2023
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Desheng HuDepartment of Integrated Traditional Chinese and Western Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Changjun YinInstitute for Cardiovascular Prevention, Ludwig-Maximilians-University Munich, Munich, Germany.
Shanshan LuoInstitute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Andreas J R HabenichtInstitute for Cardiovascular Prevention, Ludwig-Maximilians-University Munich, Munich, Germany.
Sarajo K MohantaInstitute for Cardiovascular Prevention, Ludwig-Maximilians-University Munich, Munich, Germany.
Ludwig-Maximilians-Universität München · DEHuazhong University of Science and Technology · CNUnion Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vascular smooth muscle cells (VSMCs) constitute the major cells in the media layer of arteries, and are critical to maintain the integrity of the arterial wall. They participate in arterial wall remodeling, and play important roles in atherosclerosis throughout all stages of the disease. Studies demonstrate that VSMCs can adopt numerous phenotypes depending on inputs from endothelial cells (ECs) of the intima, resident cells of the adventitia, circulating immune cells, hormones, and plasma lipoproteins. This plasticity allows them to perform multiple tasks in physiology and disease. In this minireview, we focus on a previously underappreciated activity of VSMCs, i.e., their impact on atherosclerosis immunity via formation of artery tertiary lymphoid organs (ATLOs).

Indexed as

Disease SusceptibilityImmunityAdventitiaAgingAnimalsAtherosclerosisBiomarkersCell PlasticityCytokinesEndothelial CellsHumansHyperlipidemiasInflammation MediatorsLymphocytesLymphoid TissueMiceBiomarkersCytokinesInflammation Mediatorsadventitiaartery tertiary lymphoid organsatherosclerosisendothelial cellsintimavascular smooth muscle cells

Identifiers

PMID31164888
PMCPMC6534067
OpenAlexW2945807551

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.