Evidence map›Paper›PMID 31164884›Full record

SynthesisFrontiers in immunology2019

Mechanistic Characterization of

Julio E Molineros, Bhupinder Singh, Chikashi Terao, Yukinori Okada, Jakub Kaplan, Barbara McDaniel, Shuji Akizuki, Celi Sun, Carol F Webb, Loren L Looger and 1 more

Open access · goldAbstract readMeta-Analysis
In one paragraph

Synthesis in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 2 countries.

Julio E MolinerosArthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, United States.
Bhupinder SinghArthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, United States.
Chikashi TeraoLaboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.
Yukinori OkadaDepartment of Statistical Genetics, Osaka University Graduate School of Medicine, Osaka, Japan.
Jakub KaplanArthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, United States.
Barbara McDanielArthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, United States.
Shuji AkizukiDepartment of Rheumatology and Clinical Immunology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Celi SunArthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, United States.
Carol F WebbDepartments of Medicine, Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma, OK, United States.
Loren L LoogerHoward Hughes Medical Institute, Janelia Research Campus, Ashburn, VA, United States.
Swapan K NathArthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, United States.
Oklahoma Medical Research Foundation · USJanelia Research Campus · USKyoto University · JPRIKEN Center for Integrative Medical Sciences · JPThe Institute of Statistical Mathematics · JPUniversity of Oklahoma Health Sciences Center · US

Funding

SLE Susceptibility and Clinical Significance at 2q22-24 across Multiple EthnicitiR01AR060366 · NIAMS · OKLAHOMA MEDICAL RESEARCH FOUNDATION · PI NATH, SWAPAN K. · 2010 to 2019
$3.3M
Ikaros family genes and lupus susceptibility across ethnically diverse populationsR01AI132532 · NIAID · OKLAHOMA MEDICAL RESEARCH FOUNDATION · PI GUTHRIDGE, JOEL MARVIN, NATH, SWAPAN K. · 2018 to 2021
$3.2M
Health Disparities and Genetic Architecture of Lupus in African AmericansR01MD007909 · NIMHD · OKLAHOMA MEDICAL RESEARCH FOUNDATION · PI NATH, SWAPAN K. · 2014 to 2018
$2.1M
Genetics of RASGRP1 & 3 in Lupus susceptibilityR21AR073941 · NIAMS · OKLAHOMA MEDICAL RESEARCH FOUNDATION · PI NATH, SWAPAN K. · 2018 to 2019
$423k
NIAID NIH HHS R01 AI132532NIAMS NIH HHS R01 AR060366NIAMS NIH HHS R21 AR073941NIMHD NIH HHS R01 MD007909
6 · The paper itself

Abstract

Systemic lupus erythematosus (SLE) is an autoimmune disease with a strong genetic component. We recently identified a novel SLE susceptibility locus near

Indexed as

Genetic Predisposition to DiseasePolymorphism, Single NucleotideDNA-Binding ProteinsEnhancer Elements, GeneticGuanine Nucleotide Exchange FactorsHeterogeneous-Nuclear Ribonucleoprotein KHumansLupus Erythematosus, SystemicQuantitative Trait LociDNA-Binding ProteinsGuanine Nucleotide Exchange FactorsHeterogeneous-Nuclear Ribonucleoprotein KRASGRP1 protein, humanChIP-qPCREMSA (electrophoretic mobility shift assay)ERK (extracellular-signal-regulated kinase)genetic varianthomologyluciferaseRASGRP1

Identifiers

PMID31164884
PMCPMC6536009
OpenAlexW2951258134

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.